Target List
Beta-Amyloid Generation, Oligomerization, Clearance & Degradation
Secretases
Adam9Aph1aBace1Bace2CtsbNcstnPsen1Psen2
Other Peptidases
IdePlat (tPA)Plau (uPA)Plg
Beta-Amyloid Clearance Through Endocytosis
Aplp1AppLrp1Lrp6Lrp8
Other Beta-Amyloid Metabolism Genes
A2mAcheApbb1Apbb2ApoeBcheUbqln1
Cytoskeleton Regulators
ApoeMaptMap2Pkp4Prkci
Synaptic Formation
Synaptic Transmission
Apba1 (Mint1)ApoeChat
Other Synaptic Functions
AcheApba1 (Mint1)Apbb1Apbb2ApoeBdnf
Cholesterol Metabolism
Abca1Apoa1ApoeLrp8
Lipid & Lipoprotein Metabolism
Apoa1ApoeCluHsd17b10Igf2LplLrp1Lrp8Sncb
Hormone & Hormone Processing
Bace2Igf2
Apoptosis
Induction of Apoptosis
ApoeCasp3Casp4Ern1PrkcaPrkce
Anti-Apoptotic
Il1aMpoPrkczPsen1Snca
Other Apoptosis Genes
Aplp1AppCluEp300MaptNae1Psen2
Cell Cycle
Cell Cycle Arrest
Apbb1Apbb2Ern1
Other Cell Cycle Genes
Apbb1Apbb2Cdk1 (Cdc2)Cdk5Cdkl1Nae1Ep300Il1aPrkca
Protein Kinases
Cdk1 (Cdc2)Cdk5Cdkl1Ern1Gsk3aGsk3bInsrPrkcaPrkcbPrkcgPrkcdPrkcePrkciPrkcqPrkcz
Cell Signaling Molecules
WNT Signaling
Gsk3bLrp6
Notch Signaling
Aph1aNcstnPsen1Psen2
G-Protein Coupled Receptor Signaling
Aplp2Gnao1GnazGnb1Gnb2Gnb4Gnb5Gng10Gng11Gng3Gng4Gng5Gng7Gng8Gngt1Gngt2
Intracellular Signaling
Apba3Apbb2PrkcaPrkcbPrkcgPrkcdPrkcePrkciPrkcqPrkczPsen1Psen2
Other Cell Signaling Molecules
Gap43Gnb2IdeIl1aInsrNae1Plau (uPA)
Transcriptional Regulation
Apbb1Apbb2Ep300Ern1
Other Alzheimer's Disease Genes
Oxidoreductases & Oxidative Stress
Hsd17b10MpoUqcrc1Uqcrc2
Proteases
CtscCtsdCtsgCtslUqcrc2
Protease Inhibitors
Aplp2AppSerpina3c