Target List
HIF1 & Co-Transcription Factors
ARNTCOPS5HIF1AHIF1ANHIF3AHNF4ANCOA1PER1
Other HIF1 Interactors
APEX1EGLN1EGLN2NFKB1P4HA1P4HBTP53 (p53)
Hypoxia Responsive Genes
Angiogenesis
ADORA2BANGPTL4ANXA2BTG1EDN1EGR1EPOF3GPIHMOX1JMJD6LOXMMP9PGFPLAU (UPA)SERPINE1 (PAI-1)VEGFA
Coagulation
ALDOAANXA2F10F3PLAU (UPA)SERPINE1 (PAI-1)SLC16A3
DNA Damage & Repair
ATRMIFNDRG1RUVBL2
Metabolism
ALDOADDIT4 (REDD1)ENO1ERO1A (ERO1L)GBE1GPIGYS1HK2LDHAPDK1PFKFB3PFKFB4PFKLPFKPPGAM1PGK1PKMSLC2A1SLC2A3TPI1
Regulation of Apoptosis
ADMBNIP3BNIP3LBTG1DDIT4 (REDD1)IER3MIFNOS3 (eNOS)PIM1
Regulation of Cell Proliferation
ADMBLMBTG1CCNG2EGR1IGFBP3METMIFMXI1NAMPTNOS3 (eNOS)ODC1PGFPIM1TXNIP
Transcription Factors
BHLHE40 (DEC1)FOSRBPJUSF2
Transporters, Channels & Receptors
ANKRD37SLC16A3SLC2A1SLC2A3TFRCVDAC1
Other Hypoxia Responsive Genes
CA9CTSADNAJC5EIF4EBP1 (4E-BP1)LGALS3MAP3K1 (MEKK1)