Target List
Differentiation & Development
Regulation of Differentiation & Development
AGTBDNFCTNNB1EPHB2HES1KLF10NFKBIA (IκBα, MAD3)PPARAPTHLHPTK2 (FAK)RARARHOARUNX1 (AML1)SHHTGFB2TGFBR2
Other Differentiation & Development Genes
BRD2CEBPBCREB1DNAJA1EMP1ENG (EVI-1)FN1IFRD1MAPK14 (p38ALPHA)MMP2MYOD1SNAI1 (SNAIL)
Cell Proliferation & Migration
Regulation of Proliferation & Migration
ACVRL1 (ALK1)AGTATF3BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BDNFCDC6CDKN1B (P27KIP1)CTNNB1FURINHES1HMOX1IL10KLF10MSX2MYCNFKBIA (IκBα, MAD3)PDGFAPLGPTGS2 (COX2)PTHLHPTK2B (PYK2)SERPINE1 (PAI-1)SHHSOX4TGFB2TGFBR2THBS1 (TSP-1)TXNIPVEGFA
Other Cell Proliferation & Migration Genes
ACTA2 (α-SMA)ACVR1 (ALK2)AREMP1FN1FURINIL10PTK2 (FAK)
Apoptosis
ACVR1 (ALK2)AGTAIPL1CDKN1B (P27KIP1)CREB1CTNNB1FURINGADD45BHERPUD1KLF10MAP3K7 (TAK1)MAPK8 (JNK1)MSX2PLGPTGS2 (COX2)RAD21RHOARHOBRYBPS100A8SHHSOX4TGFB2TNFSF10 (TRAIL)TXNIP
Anti-Apoptotic
BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BDNFCEBPBCRYABHMOX1IL10NFKBIA (IκBα, MAD3)PTK2B (PYK2)THBS1 (TSP-1)VEGFA
Cell Cycle
Regulation of the Cell Cycle
ACVR1 (ALK2)RAD21
Other Cell Cycle Genes
CDC6CDKN1B (P27KIP1)GADD45BPTGS2 (COX2)RHOBTGFB2
Signal Transduction
TGFβ Signaling
ACVR1 (ALK2)ACVRL1 (ALK1)CREBBP (CBP)E2F4ENG (EVI-1)EP300ID1ID2ID3MSX2RBL1SMAD1 (MADH1)SMAD3 (MADH3)SMAD5 (MADH5)SMAD6SP1TGFB2TGFBR2THBS1 (TSP-1)
NFκB Signaling
HMOX1IL10MAP3K7 (TAK1)NFKBIA (IκBα, MAD3)RHOATNFSF10 (TRAIL)
Notch Signaling
HES1HEY1NOTCH1
Hedgehog Signaling
GLI2SHH
WNT Signaling
CTNNB1
Transcription Factors
TGFβ Signaling
CREBBP (CBP)E2F4EP300ID1ID2ID3RBL1SMAD1 (MADH1)SMAD3 (MADH3)SMAD5 (MADH5)SMAD6SP1
Other Transcription Factors
ARATF3ATF4BACH1BHLHE40 (DEC1)CEBPBCREB1CTNNB1FOSGTF2IHEY1KLF10MBD1MSX2MYCMYOD1NFIBPPARARARARUNX1 (AML1)SOX4SREBF2