Target List
Insulin Receptor-Associated Proteins
Insulin & Receptors
Ins1Ins2Insl3Irs1Irs2
Insulin-Like Growth Factors & Receptors
Grb10Igf1rIgf2Igfbp1
SH3 / SH2 Adaptor Proteins
CblGab1Grb10Grb2
Other Insulin Receptor-Associated Proteins
Cap1Dok1Dok2Dok3Frs2Frs3InsrPdpk1Ppp1caPtpn1 (Ptp)Shc1
PI3 Kinase Signaling
PI3 Kinase Canoncial Pathway Genes
Akt1Akt2Akt3Eif2b1Eif4ebp1Gsk3bMtorPdpk1Pik3ca (p110-alpha)Pik3cbPik3r1 (PI3KA)Pik3r2PrkcgPrkcz
PI3 Kinase Signaling Target Genes
Adra1dBcl2l1 (Bcl-xl)Bcl2l1 (Bcl-xl)Bcl2l1 (Bcl-xl)Dusp14G6pcHk2Igfbp1Pck2Serpine1 (Pai-1)Slc2a4 (Glut4)Srebf1Ucp1Vegfa
MAP Kinase Signaling
MAP Kinase Canoncial Pathway Genes
ArafBrafEif2b1Grb2HrasKrasMap2k1 (MEK1)Mapk1 (Erk2)Raf1Rps6ka1RrasRras2Shc1Sos1
MAP Kinase Signaling Target Genes
Bcl2l1 (Bcl-xl)Bcl2l1 (Bcl-xl)Bcl2l1 (Bcl-xl)Ercc1FosLdlrNos2 (Nos2a, iNos)Ucp1
Primary Insulin Signaling Target Genes
CebpaCebpbFosGcgJunLep (Leptin)Prl
Secondary Insulin Signaling Effector Target Genes
LOC100912228 (Npy)Pck2Slc2a1Slc2a4 (Glut4)Tg
PPARγ Targets
Acox1Aebp1Cap1CebpaCebpbCfdGpd1Pck2PpargRetnSlc27a4
SREBP1 Targets
AcacaFbp1G6pcGckPck2Pklr
Carbohydrate Metabolism
Glucose Metabolism
Fbp1G6pcGckGpd1Hk2Ins1Irs2Pck2PklrSlc2a1Slc2a4 (Glut4)
Glycogen Metabolism
G6pcGsk3bPpp1ca
Carbohydrate Transport
Ins1Slc2a1Slc2a4 (Glut4)
Lipid Metabolism
Cholesterol Metabolism
LdlrSrebf1
Fatty Acid Metabolism
AcacaAcox1FasnSlc27a4
Lipid Transport
LdlrSlc27a4
Other Lipid Metabolism Genes
ArafBrafIns1Lep (Leptin)PpargPrkczRaf1Shc1
Protein Metabolism
Protein Phosphatases
Dusp14Ppp1caPtpn1 (Ptp)
Protein Kinases
Akt1Akt2Akt3ArafBrafGsk3bIgf1rInsl3InsrMap2k1 (MEK1)Mapk1 (Erk2)Pdpk1PrkcgPrkczRaf1Rps6ka1
Protein Biosynthesis
Eif2b1Eif4ebp1LdlrPpp1ca
Protein Transport
Gsk3bHrasRras2
Other Protein Metabolism Genes
Aebp1CblDok1Dok2Frs2Gab1Grb10Irs1Nos2 (Nos2a, iNos)Vegfa
Transcription Factors & Regulators
Transcriptional Regulation
CebpaCebpbFosJunPpargSrebf1
Transcription Factors
Aebp1CblCebpaCebpbFosJunKlf10PpargSrebf1
Cell Growth & Differentiation
Cell Cycle
Hk2HrasIgf1rIgf2KrasMapk1 (Erk2)MtorVegfa
Cell Proliferation
Gab1Igf1rIgf2Irs2LOC100912228 (Npy)PrlRaf1Shc1Vegfa
Growth Factors & Receptors
Gab1Grb2Igf1rIgf2Igfbp1InsrShc1Vegfa
Cell Differentiation
Nos2 (Nos2a, iNos)Pparg