Target List
Oxidative Stress
FTH1GCLCGCLMGSRGSTP1HMOX1NQO1PRDX1SQSTM1TXNTXNRD1
Hypoxia Signaling
ADMARNTBNIP3LCA9EPOHMOX1LDHAMMP9SERPINE1 (PAI-1)SLC2A1VEGFA
Osmotic Stress
AKR1B1AQP1AQP2AQP4CFTREDN1HSPA4L (OSP94)NFAT5SLC5A3
Cell Death
Apoptosis
CASP1 (ICE)FASMCL1TNFRSF10A (TRAIL-R)TNFRSF10B (DR5)TNFRSF1A (TNFR1)
Autophagy
ATG12ATG5ATG7BECN1FASULK1
Necrosis
FASGRB2PARP1 (ADPRT1)PVRRIPK1TNFRSF10A (TRAIL-R)TNFRSF1A (TNFR1)TXNL4B
Inflammatory Response
CCL2 (MCP-1)CD40LGCRPCXCL8 (IL8)IFNGIL1AIL1BIL6TLR4TNF
DNA Damage & Repair
Cell Cycle Arrest & Checkpoints
CDKN1A (p21CIP1, WAF1)CHEK1CHEK2 (RAD53)DDIT3 (GADD153, CHOP)HUS1MRE11NBNRAD17RAD9A
Other DNA Damage Responses
ATMATRDDB2GADD45AGADD45GRAD51TP53 (p53)XPC
Unfolded Protein Response
ATF4ATF6ATF6BBBC3 (PUMA)BIDCALRDDIT3 (GADD153, CHOP)DNAJC3HSP90AA1HSP90B1HSPA4 (HSP70)HSPA5 (GRP78)