Target List
Beta-Amyloid Generation, Oligomerization, Clearance & Degradation
Secretases
Adam9Aph1aBace1Bace2CtsbNcstnPsen1Psen2
Other Peptidases
IdePlat (tPA)Plau (UPAM)Plg
Beta-Amyloid Clearance Through Endocytosis
AppLrp1Lrp6
Other Beta-Amyloid Metabolism Genes
AcheApbb1Apbb2ApoeBcheLOC100911545 (A2m)Ubqln1
Cytoskeleton Regulators
ApoeMap2MaptPkp4Prkci
Synaptic Formation
Synaptic Transmission
Apba1 (Mint1)ApoeChat
Other Synaptic Functions
AcheApba1 (Mint1)Apbb1Apbb2ApoeBdnf
Cholesterol Metabolism
Abca1Apoa1Apoe
Lipid & Lipoprotein Metabolism
Apoa1ApoeCluHsd17b10Igf2Il1bIns2LplLrp1Sncb
Hormone & Hormone Processing
Bace2Igf2Ins2
Apoptosis
Induction of Apoptosis
ApoeCasp3Casp4Ppp3ccPrkcaPrkce
Anti-Apoptotic
Il1aIl1bMpoPrkczPsen1Snca
Other Apoptosis Genes
AppCluEp300 (QuantiNova Symbol: AABR07058539.1)MaptNae1Psen2
Cell Cycle
Cell Cycle Arrest
Apbb1Apbb2
Other Cell Cycle Genes
Apbb1Apbb2Cdk1Cdk5Cdkl1Ep300 (QuantiNova Symbol: AABR07058539.1)Il1aNae1Prkca
Protein Kinases
Cdk1Cdk5Cdkl1Gsk3aGsk3bInsrPrkcaPrkcbPrkcdPrkcePrkcgPrkciPrkcqPrkcz
Cell Signaling Molecules
WNT Signaling
Gsk3bLrp6
Notch Signaling
Aph1aNcstnPsen1Psen2
G-Protein Coupled Receptor Signaling
Aplp2Gnao1GnazGnb1Gnb2Gnb4Gnb5Gng10Gng11Gng5Gng7Gng8
Intracellular Signaling
Apba3Apbb2PrkcaPrkcbPrkcdPrkcePrkcgPrkciPrkcqPrkczPsen1Psen2
Other Cell Signaling Molecules
Gap43Gnb2IdeIl1aIl1bInsrNae1Plau (UPAM)
Transcriptional Regulation
Apbb1Apbb2Ep300 (QuantiNova Symbol: AABR07058539.1)
Other Alzheimer's Disease Genes
Oxidoreductases & Oxidative Stress
Hsd17b10MpoMt3Ndufb8Uqcrc1Uqcrc2
Proteases
Capn1CtscCtsdCtsgCtslUqcrc2
Protease Inhibitors
Aplp2AppLOC299282 (QuantiNova Symbol: Serpina3n)Serpina3c