Target List
Notch Signaling
Notch Ligands
Notch1Notch2Notch3Notch4
Notch Binding
Dll1 (Delta1)Dll3Dll4Dvl1Jag1Jag2LfngMfngNumbRfng
Notch Receptor Processing
Adam10Adam17 (Cd156b)Aph1aNcstnPsen1Psen2Psenen
Transcription Factors & Cofactors
Ep300 (QuantiNova Symbol: AABR07058539.1)Hdac1Kat2b (QuantiNova Symbol: AABR07066180.1)Maml1Ncor2Rbpjl
Notch Target Genes
Apoptosis
Cflar (Casper)Id1IfngNfkb1Ptcra
Cell Cycle
Ccnd1Cdkn1a (Cip1, Waf1)
Cell Adhesion Molecules
Cd44Erbb2 (Her-2, neu)
Cell Differentiation & Development
Hes1Hes5Hey1Hey2HeylJag1Krt1LfngNotch1Nr4a2 (Nurr1)Pparg
Neurogenesis
Erbb2 (Her-2, neu)FosHes1Hey1Nr4a2 (Nurr1)
Immune Response
Chuk (Ikbka, Ikka)IfngIl17bIl2ra (Cd25)Nfkb1Nfkb2Stat6
Transcription Factors & Cofactors
FosFosl1 (Fra-1)Hes1Hes5Hey1Hey2HeylId1Nfkb1Nfkb2Nr4a2 (Nurr1)PpargStat6
Other Notch Signaling Genes
Cell Cycle
Ccne1Gsk3bVegfd (Vegfd)
Cell Growth & Migration
Ccn4Lrp5Shh
Cell Proliferation & Differentiation
Ctnnb1Gsk3bIl6st (Gp130)Lmo2Mmp7Runx1 (Aml1)ShhVegfd (Vegfd)
Neurogenesis
Neurl1 (Neu1)Pofut1Zic2 (Hpe5)
Transcription Factors & Cofactors
Aes (Tle5, Groucho)CblCtnnb1Gli1Hoxb4hrRunx1 (Aml1)Tle1
Other Notch Signaling Genes
Gbp2Sel1lSupt6h
Pathways Crosstalking with Notch Signaling
Hedgehog Signaling
Gli1Gsk3bShhSmoSufu
WNT Signaling
Aes (Tle5, Groucho)Ccn4Ctnnb1Fzd2Fzd3Fzd4Fzd5Fzd6Fzd7Gsk3bLrp5Tle1Wnt1Wnt11