Target List
Insulin Signaling
Akt3Gys1Igf1Igf1rIkbkb (IKK2)InsrIrs1Irs2Map2k1 (MEK1)Mapk3 (ERK1)Mapk9 (Jnk2)MtorPde3bPik3ca (p110-alpha)Pik3r1 (PI3KA)Ppargc1aPtpn1 (Ptp)Rps6kb1Slc2a4 (Glut4)Socs3Srebf1
Non-Insulin Dependent Diabetes Mellitus
AdipoqHk2Ikbkb (IKK2)InsrIrs1Irs2LOC103694380 (Tnf)Mapk3 (ERK1)Mapk9 (Jnk2)MtorPdx1 (Ipf1)Pik3ca (p110-alpha)Pik3r1 (PI3KA)Slc2a4 (Glut4)Socs3
Adipokine Signaling
Adipokines
AdipoqIl6Lep (Leptin)LOC103694380 (Tnf)NamptRetnSerpine1 (Pai-1)
Receptors & Transporters
Adipor1Adipor2Cd36 (QuantiNova Symbol: RGD1565355)LeprSlc2a4 (Glut4)Tnfrsf1a (Tnfr1)Tnfrsf1b
Signaling Downstream of Adipokines
Akt3Chuk (Ikbka, Ikka)Ikbkb (IKK2)Irs1Irs2Jak2Mapk9 (Jnk2)MtorNfkbia (Iκbα, Mad3)PparaPpargc1aRelaSocs3Stat3
Innate Immunity
Casp1 (Ice)Chuk (Ikbka, Ikka)Ikbkb (IKK2)Irs1Irs2Nfkbia (Iκbα, Mad3)Nlrp3Pycard (Tms1, Asc)RelaTlr4
Inflammation
Alox5Casp1 (Ice)Ccl12Ccr4Ccr5Chuk (Ikbka, Ikka)Cxcr4IfngIkbkb (IKK2)Il1bIl23rIl6LOC103694380 (Tnf)Lta4hNlrp3Olr1Pycard (Tms1, Asc)RelaTnfrsf1a (Tnfr1)Tnfrsf1b
Apoptosis
Casp1 (Ice)Ikbkb (IKK2)Irs2Jak2LOC103694380 (Tnf)Mapk9 (Jnk2)Nfkbia (Iκbα, Mad3)Nlrp3Pik3ca (p110-alpha)PpargPycard (Tms1, Asc)RelaRps6kb1Serpine1 (Pai-1)Socs3Tnfrsf1a (Tnfr1)Tnfrsf1b
Metabolic Pathways
Carbohydrate Metabolism
CsGys1Hk2Pck1Pdk2
Lipid Metabolism
AcacaAcacbAcsl1Acsl4ApoeCebpaCnbpFabp4FasnLeprLipeLplPparaPpargPpargc1aScdSrebf1Srebf2
Metabolite Transport
ApoeCd36 (QuantiNova Symbol: RGD1565355)Fabp4Rbp4Slc27a1Slc2a4 (Glut4)Ucp1Vldlr
Infiltrating Leukocyte Markers
Macrophages
Adgre1Ccr5Cxcr4
Th1 Cells
Ccr5Cd3eCxcr3Il18r1
Th2 Cells
Ccr4Cd3eCrlf2Il1r1
Th17 Cells
Ccr6Cd3eIl23r