Target List
Unfolded Protein Binding
CalrCanxCct4Cct7Dnajb9Dnajc10Dnajc4Hspa2Hspb9Htra2Pfdn5Pfdn6PpiaScapSec63Sil1Tcp1Tor1aUggt1
Endoplasmic Reticulum Protein Folding Quality Control
Edem1GanabPrkcshRpn1Serp1Uggt1
Regulation of Cholesterol Metabolism
Insig1Insig2Mbtps1Mbtps2ScapSrebf1Srebf2
Regulation of Translation
Eif2aEif2ak2Eif2ak3Eif2ak4Ppp1r15a (Gadd34)Ppp1r15bSerp1
Endoplasmic Reticulum Associated Degradation (ERAD)
Derl1Edem1Edem2Fbxo6Herpud1Herpud2Htra2Htra4Mbtps1Mbtps2Nploc4Nucb1Os9Sec62Sel1lSelenosSyvn1Ubxn4Vcp
Ubiquitination
Herpud1Rnf139Sec62Sel1lUbe2g2Ube2j2Ubxn4Ufd1Usp14Vcp
Transcription Factors
Atf4Atf6Atxn3CalrCebpbCreb3Creb3l1Creb3l2Creb3l3Creb3l4Ddit3 (Gadd153, Chop)Ern2Mbtps1Pfdn5ScapSrebf1Srebf2Xbp1
Protein Folding
CalrCanxCct4Cct7Dnajb9Dnajc10Dnajc4Ero1aHsp90b1Hspa4lPfdn5PpiaPpibPpicSec63Sil1Tcp1Tor1aUggt1
Protein Disulfide Isomerization
Ddit3 (Gadd153, Chop)Dnajc10Ero1aPdia3SelenosSrebf1
Heat Shock Proteins
Dnajb9Dnajc10Dnajc3Dnajc4Hspa1lHspa4 (Hsp70)Hspa5 (Grp78)Hsph1Sec63
Apoptosis
Atxn3BaxCalrCebpbDdit3 (Gadd153, Chop)Eif2ak2Eif2ak3Ern2Hspb9Htra2ManfMapk10 (Jnk3)Mapk8 (Jnk1)Mapk9 (Jnk2)Pdia3Ppp1r15a (Gadd34)Ppp1r15bSelenosVcp