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GeneGlobe ID: JHS-004Z | Cat. No.: | QIAseq RNA Fusion XP Panels

RNA Fusion XP Lymphoma Panel

Kit containing ALL reagents (except indexes) for fusion and gene expression profiling by digital RNAseq

Select a variant to see the price

Product Specification

Target List

Acute Lymphoblastic Lymphomas
CREBBP (CBP)KMT2AMLLT10MYCP2RY8PRDM16STIL
Anaplastic Large Cell Lymphomas
ADGRG7ALKATICCLTCMSNMYCNPM1TFGTPM3TPM4ALKCDKN2A (P16INK4A)DNMT3ANRASSTAT3
Angioimmunoblastic T Cell Lymphomas
CD28CTLA4FIP1L1PDGFRAALKAPCARID1AASXL1ATMBRAFCDKN2A (P16INK4A)CREBBP (CBP)CTNNB1DNMT3AEZH2FBXW7IDH2JAK1JAK3KIT (CD117)KMT2DKRASMED12PLCG1RHOASTAT3WT1XPO1ZFHX3
Burkitt Lymphomas
BCL6MYCPBX1TCF3APCARID1AATMCD79BCDKN2A (P16INK4A)CREBBP (CBP)FBXW7HLA-AID3KRASMYCMYD88NRASPAX5PIK3CA (p110-alpha)PIK3R1 (p85-ALPHA)PTENRHOASRSF2
Diffuse Large B Cell Lymphomas (DLBCL)
ALKBCL11ABCL6CCND3CIITACLTCIGLL5MAPK13 (p38delta)MYCNPM1PIM1RELSQSTM1TBL1XR1TOMM40TP63ALKAMER1APCARID1AASXL1ATMB2MBCL2BCORBRAFBTKCD79BCDKN2A (P16INK4A)CNOT3CREBBP (CBP)CTNNB1CXCR4DNMT3AEZH2FBXW7HLA-AID3IDH2IRS4JAK1JAK3KIT (CD117)KMT2DKRASMAP2K1MED12MSNMYCMYD88NCOR1NFKBIENOTCH2NRASNSD2PAX5PIK3CA (p110-alpha)PIK3R1 (p85-ALPHA)PLCG1POT1PPM1DPTENRGS7RHOASF3B1SMOSRSF2STAT3STAT5BSTAT6TERTTRRAPWT1XPO1ZFHX3ZNF479
Follicular Lymphomas
AFF3BCL2BCL6CIITAMYCTBL1XR1TP63AMER1ARID1AATMB2MBCL2BCORBRAFBTKCD79BCDKN2A (P16INK4A)CREBBP (CBP)CXCR4DNMT3AEZH2FBXW7ID3IDH2KMT2DMAP2K1MED12MYD88NOTCH2NRASPIK3R1 (p85-ALPHA)PPM1DPTENRGS7RHOASRSF2STAT6ZMYM3
Hodgkin Lymphomas
ALKCIITAJAK2NPM1SEC31AARID1AASXL1B2MBCORCDKN2A (P16INK4A)DNMT3AEZH2NFKBIENRASPAX5PIK3R1 (p85-ALPHA)PPM1DSF3B1
Inflammatory Myofibroblastic Tumors
ALKDCTN1
Lymphoblastic Lymphomas
BCRETV6FGFR1NOTCH1PBX1
Lymphoblastic T Cell Lymphomas
BCRETV6FGFR1FIP1L1LYNPDGFRA
Mantle Cell Lymphomas
CCND3MYCARID1AASXL1ATMB2MBCORBRAFBTKCDKN2A (P16INK4A)CREBBP (CBP)DNMT3AIDH2KMT2DKRASMED12NCOR1NFKBIENOTCH2NRASNSD2PAX5POT1PPM1DPTENSTAT3TERTZFHX3
Mediastinal Large B Cell Lymphomas (MLBL)
CIITAPDCD1LG2
Mediastinal Large B-Cell Lymphomas
CIITAPDCD1LG2
Mucosa-Associated Lymphoid Tissue (MALT) Lymphomas
BCL6BIRC3 (c-IAP2)CCND3MALT1MYCMYD88NOTCH2
Peripheral T Cell Lymphomas
ALKETV6FGFR3ITKMYO1FNPM1S100A7SYKTBL1XR1THAP4TP63VAV1ALKARID1AASXL1ATMCDKN2A (P16INK4A)CTNNB1DNMT3AIDH2IRS4KIT (CD117)KMT2DKRASMAP2K1MSNNRASPLCG1PTENRGS7RHOASTAT3STAT5BTRRAPXPO1ZFHX3ZNF479
Precursor T Cell Lymphoblastic Lymphomas
ABL1JAK2NUP214PCM1SETCTNNB1FBXW7NRASWT1
T Cell Lymphomas
ATXN2LFGFR1JAK2
Other Lymphomas
ALKATXN2LBCL6BIRC3 (c-IAP2)CBFBCCND1CCND3CDK6CHIC2CLTCDEKDUSP22EIF4A1JAK2KMT2AMALT1MKL1MLF1MLLT10NFKB2NPM1PRDM16
Commercial Control Samples
ALKBAIAP2L1BRAFCCDC6CD74EGFR (ERBB1)EML4ERGETV6FGFR3KIF5BLMNAMETNCOA4NTRK1NTRK3PAX8PPARGRETROS1SEPT14SLC34A2SLC45A3TACC3TFGTMPRSS2TPM3
Checkpoint Molecules
Inhibitory on Tumor Cells​
CD200CD274 (PD-L1)CD274 (PD-L1)CD48CD80CD86ITGAVITGB3LGALS9MICAMICBPDCD1LG2TNFRSF14VSIR
Stimulatory on Tumor Cells​
CD40 (TNFRSF5)CD40LGCD48CD70CD86ICOSLGTNFRSF9TNFSF14TNFSF4 (OX40L)TNFSF9
Inhibitory on T Cells​
BTLACD160CD200R1CD244CD274 (PD-L1)CD274 (PD-L1)CD28CTLA4HAVCR2KLRC1LAG3LILRB1LILRB3PDCD1 (PD1)PDCD1 (PD1)VSIR
Stimulatory on T Cells​
CD244CD27 (TNFRSF7)CD28CD40 (TNFRSF5)CD40LGICOSTNFRSF14TNFRSF18TNFRSF4 (OX40)TNFRSF9TNFSF14TNFSF9
T Cell Receptor Genes​
CD247CD3DCD3ECD3GTRACTRGC2
Major Histocompatibility Complex I Genes​
B2MHLA-AHLA-BHLA-CHLA-EHLA-FHLA-GHLA-HMR1
Major Histocompatibility Complex II Genes​
CD74HLA-DMAHLA-DMBHLA-DOAHLA-DOBHLA-DPA1HLA-DPB1HLA-DQA1HLA-DQA2HLA-DQB1HLA-DQB2HLA-DRAHLA-DRB1HLA-DRB5IFI30
Other Checkpoint Molecules​
ADORA2ABTNL2CD160CD276CD44CD52CD8AHHLA2IDO1 (IDO)IDO1 (IDO)IDO2KIR3DL1KLRD1LAIR1MS4A1NRP1TIGITTMIGD2TNFRSF25 (DR3)TNFRSF8TNFSF15VTCN1
Checkpoint Blockade Therapy Biomarkers
BTLACD274 (PD-L1)CD274 (PD-L1)CD80CD8ACSF2 (GM-CSF)CXCL11 (I-TAC, IP-9)HAVCR2HLA-DRAHLA-DRB1HLA-DRB5ICOSIFNGLAG3PDCD1 (PD1)PDCD1 (PD1)PDCD1LG2
Immuno Regulatory Gene Signature
ERBB2 (HER-2, NEU)FASIL5RA (CD125)INHBATNFRSF8TNFSF4 (OX40L)TNFSF9
Immuno Stimulatory Gene Signature
CD160CD19CD200CD27 (TNFRSF7)CD44CTLA4HLA-AIL12RB2IL17AKIT (CD117)TNFRSF17
Immuno Suppressive Gene Signature
CD274 (PD-L1)CD274 (PD-L1)CD276HAVCR2PDCD1LG2TGFB1
Upregulated in Cancer Vaccination Response
CCL5 (RANTES)CD3DCD86CD8ACXCL10 (INP10)CXCL9 (MIG)GBP1ICOSIRF1KLRD1PSMB9STAT1
Immune Cell Markers
CD8 T Cells​
CD8ACD8BFLT3LGGZMMPRF1
Th1 Cells​
CCL4 (MIP-1B)CD38CD70CSF2 (GM-CSF)CTLA4DPP4IFNGIL12RB2LTA (TNFB)STAT4TBX21
Th17 Cells​
IL17AIL17RARORC
Th2 Cells​
CXCR6GATA3IL26LAIR2MAFPMCHSMAD2 (MADH2)STAT6
Follicular Helper T Cells​
BCL6CXCL13MAFPDCD1 (PD1)PDCD1 (PD1)
Other T Helper Cell Markers​
ANP32BBATFCD28ICOSNUP107
Regulatory T Cells​
FOXP3
Gamma Delta T Cells​
CD160FEZ1TRGC1
Central Memory T Cells​
ATMDOCK9FYB1NEFLREPS1TXKUSP9Y
Effector Memory T Cells​
AKT3CCR2EWSR1IL15RALTKNFATC4 (NFAT3)
Other T Cell Markers​
CD2CD247CD3DCD3ECD3GCD6IL2RBTNFRSF25 (DR3)TRACTRGC2
Myeloid Derived Suppressor Cells​
TGFB1
Cytotoxic Lymphocytes​
CD3ECD3GCD8ACD8BEOMESGZMAGZMBIFNGKLRC1KLRD1NKG7TBX21
Natural Killer Cells​
BCL2CD160FOXJ1FUT5GTF3C1GZMBIL21RKIR3DL1MPPED1NCR1PLA2G6RRADZNF205
Activated Dendritic Cells​
CCL1 (I-309)EBI3LAMP3OAS3
Immature Dendritic Cells​
CD1ACD1BCD1EF13A1SYT17
Myeloid Dendritic Cells​
CD1ACD1BCD1E
Plasmacytoid Dendritic Cells​
IL3RA
Other Dendritic Cell Markers​
CCL13 (MCP-4)CCL17 (TARC)CCL22 (MDC)CD209HSD11B1
Macrophages​
APOECCL7 (MCP-3)CD68CHIT1CXCL5 (ENA-78, LIX)MARCOMSR1
Neutrophils​
CSF3R (GM-CSFR)FPR2MME
Eosinophils​
CCR3IL5RA (CD125)PTGDR2 (CRTH2, GPR44)SMPD3THBS1 (TSP-1)
Mast Cells​
CMA1CTSGKIT (CD117)MS4A2PRG2TPSAB1
B Cells​
BANK1BLKCD19CD79ACR2HLA-DOBHLA-DQA1MS4A1PAX5TNFRSF17
Antigen Presenting Cells​
CMKLR1
Regulatory T Cell Gene Signature
CD274 (PD-L1)CD274 (PD-L1)JAK1PDCD1LG2TIGITTNFRSF18TNFRSF4 (OX40)TNFRSF8TNFRSF9
T Cell Trafficking & Infiltration into Tumors
Stimulates T Cell Trafficking & Infiltration into Tumors​
CCL5 (RANTES)CX3CL1CXCL10 (INP10)CXCL9 (MIG)ITGB2SELL (LECAM-1)
Other T Cell Trafficking & Infiltration into Tumors Genes​
CCL17 (TARC)CCL4 (MIP-1B)CCR3CCR6CD274 (PD-L1)CD274 (PD-L1)CD44CSF2 (GM-CSF)CXCL11 (I-TAC, IP-9)CXCL13FOXP3IFNGITGA4 (CD49D)ITGB7LTA (TNFB)PDCD1 (PD1)PDCD1 (PD1)PDCD1LG2PTENTNFRSF25 (DR3)TNFSF14
T Cell Exhaustion
Upregulated in T Cell Exhaustion​
CCL5 (RANTES)CD200CD27 (TNFRSF7)CD69CTLA4CXCL10 (INP10)CXCL13GBP1HLA-DMAHLA-DQA1ICOSIFI16IFNGITGAVTAP1 (ABCB2)TIGITTNFRSF9
Downregulated in T Cell Exhaustion​
TNFRSF25 (DR3)
T Cell Exhaustion Transcriptional Nodes​
BATFTBX21
Responsiveness or Response Biomarkers
Enhanced Expression in Responsive Versus Nonresponsive Cancers​
APPCAPZBCCL4 (MIP-1B)CCL5 (RANTES)CD8ACSNK1ECTLA4CXCL10 (INP10)CXCL11 (I-TAC, IP-9)CXCL9 (MIG)EBI3EHD1GBA2GZMBHLA-DQA1IDO1 (IDO)IDO1 (IDO)IFNGINHBAIRF2NKG7ODF2PHKG2PPIFPRF1SERPINA3SHMT2SIGMAR1SMAD3 (MADH3)TIA1
Suppressed Expression in Responsive Versus Nonresponsive Cancers​
ACTG1BNIP3LCX3CL1FOXN3IFI27JAK1LTA4HNAIPOPTNPRRC2BPTENRBL2TXK
Differentially Expressed in Responsive Versus Nonresponsive Cancers​
ADAM28AKNAAOAHARHGAP9CACNA2D2CARD11CARD16CD109CLEC11ACORO1ACORO1BCXCR4FLT3FMNL1HIVEP1HIVEP2IFI44LIFITM1 (9-27)IGHA1IGHMIGSF6IKZF1ITPKALSM4LST1MAP3K14NFAM1NFKBIL1PLA2G2DPOU2AF1 (OCA-B)PTPRCAPSERPINB9SH3BP5SYTL1TMC8TNFRSF13BTNFRSF19ZFYVE9
Expression Correlates with Positive Objective Response Rates​
CD274 (PD-L1)CD274 (PD-L1)CD276CTLA4HAVCR2IDO1 (IDO)IDO1 (IDO)LAG3PDCD1LG2VTCN1
Upregulated during Treatment​
CD8ACTLA4CXCL10 (INP10)EOMESGZMAGZMBICOSIFNGPRF1
Regulated during Treatment​
IRF1
Pre-Treatment Response Prediction
Predicts Enhanced Response​
ADAM17 (CD156B)MYCRHOCTIMP1
Other Pre-Treatment Response Predictors​
CDK2CDKN2A (P16INK4A)LARGE1NAB2NRAS
Cancer Cell Killing
Inhibits Cancer Cell Killing​
BTLACD274 (PD-L1)CD274 (PD-L1)CD80HAVCR2IDO1 (IDO)IDO1 (IDO)IDO2LAG3MICAMICBPDCD1 (PD1)PDCD1 (PD1)TGFB1VSIRVTCN1
Stimulates Cancer Cell Killing​
IFNG
Antigen Processing & Presentation
Proteasome​
PSMB10PSMB9
Proteases​
IFI30
Endoplasmic Reticulum & Lysosomal Transport​
TAP1 (ABCB2)TAP2 (ABCB3)TAPBPL
Major Histocompatibility Complex I Genes​
B2MHLA-AHLA-BHLA-CHLA-EHLA-FHLA-GHLA-HMR1
Major Histocompatibility Complex II Genes​
CD74HLA-DMAHLA-DQA1HLA-DRAHLA-DRB1HLA-DRB5IFI30
Immune Cell Receptors & Co-Receptors​
CD8ACD8BKIR3DL1KLRC1KLRD1
Stimulates Antigen Presentation​
CD40 (TNFRSF5)CD40LG
Interferon Gamma Response
Cytokines & Chemokines​
CCL5 (RANTES)IL15RASTAT1
Major Histocompatibility Complex I Genes​
B2MHLA-AHLA-BHLA-CHLA-EHLA-FHLA-GHLA-H
Major Histocompatibility Complex II Genes​
HLA-DMAHLA-DQA1HLA-DRAHLA-DRB1HLA-DRB5IFI30
RNA Degradation​
OAS3
Transcription Factors​
IRF1IRF2
Other Interferon Gamma Response Genes​
CD44GBP1
Cytosolic DNA-Sensing Pathway
Cytokines & Interferons​
CCL4 (MIP-1B)CCL5 (RANTES)CXCL10 (INP10)
Expression Altered due to Genetic Alterations
BCL10BCL2BCL3BCL6BCL9CCND1CCND2CCND3CD44CDK6ERVW-1FCGR2BFCRL4FOXP1GPR34IRF4KDSRMALT1MTCP1MUC1 (mucin)MYCNBEAP1NFKB2PAX5PRDM16
AIDS-Related Lymphomas
EZH2
B Cell Lymphomas
ARID1AATMB2MBCL2BCORBRAFCD79BCDKN2A (P16INK4A)CREBBP (CBP)CTNNB1CXCR4DNMT3AEZH2JAK3KIT (CD117)KMT2DMAP2K1MYD88PIK3CA (p110-alpha)PPM1DPTENRHOASTAT3
Small Lymphocytic Lymphomas
ALKAPCARID1AASXL1ATMBCL2BCORBRAFBTKCD79BCDKN2A (P16INK4A)CNOT3CREBBP (CBP)CXCR4DNMT3AFBXW7GNASIRS4JAK1JAK3KIT (CD117)KMT2DKRASMAP2K1MED12MSNMYCMYD88NCOR1NFKBIENOTCH2NRASPAX5PIK3CA (p110-alpha)PIK3R1 (p85-ALPHA)PLCG1POT1PPM1DPTENRGS7SF3B1STAT5BSTAT6TERTTRRAPXPO1ZFHX3ZMYM3ZNF479
Cutaneous T Cell Lymphomas
KRASPTEN
Diffuse Red Pulp Small B Cell Lymphomas
MYD88NOTCH2
Enteropathy-Type T Cell Lymphomas
STAT5B
Gamma-Delta T Cell Lymphomas
STAT3STAT5B
Hepatosplenic T Cell Lymphomas
STAT3STAT5B
Lymphoplasmacytic Lymphomas
ARID1ABTKCD79BCXCR4DNMT3AMYD88
Marginal Zone Lymphomas
AMER1ARID1AASXL1ATMBRAFCD79BCREBBP (CBP)CXCR4DNMT3AEZH2FBXW7GNASJAK3KIT (CD117)KMT2DMAP2K1MYD88NFKBIENOTCH2PIK3R1 (p85-ALPHA)RHOASRSF2TRRAPXPO1
Mycosis Fungoides (Sezary Syndrome)
AMER1ARID1AATMBCORCDKN2A (P16INK4A)DNMT3AJAK1JAK3KMT2DKRASNCOR1NRASPIK3CA (p110-alpha)PLCG1POT1PTENSTAT3STAT5B
NK-T Cell Lymphomas
ALKAMER1APCARID1AASXL1ATMB2MBCORBRAFCTNNB1DNMT3AEZH2FBXW7HLA-AJAK1JAK3KIT (CD117)KMT2DKRASMED12NCOR1NOTCH2NRASPOT1RGS7RHOASMOSTAT3STAT5BWT1XPO1ZFHX3
Primary Central Nervous System Lymphomas
B2MBCL2CD79BCDKN2A (P16INK4A)CXCR4DNMT3AHLA-AJAK3KIT (CD117)KRASMYD88NOTCH2POT1STAT3STAT5BTERTTRRAPWT1
Primary Effusion Lymphomas
CDKN2A (P16INK4A)PTEN

Product Resources

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Resources

Brochures & Guides (2)
Massively Parallel Sequencing Solutions for Human Identity
PDF (2MB)

Next-generation sequencing using QIAGEN’s QIAseq – a powerful tool for human identification


The QIAseq advantage – interactive product profile
PDF (2MB)
State-of-the-art technologies to fast-track and streamline NGS workflows
Application Notes (2)
Noninvasive prenatal paternity testing by means of SNP-based targeted sequencing barcoded with Unique Molecular Indices
PDF (435KB)

The use of UMIs as part of a QIAseq targeted sequencing panel

QIAseq SPE technology for Illumina: Redefining amplicon sequencing
PDF (238KB)
Safety Data Sheets (2)
Safety Data Sheets
Download Safety Data Sheets for QIAGEN product components.
QIAseq 8-UDI Kit Set D (48)
Kit Handbooks (1)
QIAseq RNA Fusion XP Panel Handbook
PDF (3MB)
Template Files (1)
QIAseq RNA Fusion XP All-in-One Tool
SOFTWARE (884KB)
Certificates of Analysis (1)
Certificates of Analysis
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