Target List
Pro-Fibrotic
Acta2AgtCcl11Ccl12Ccl3Ccn2Grem1Il13Il13ra2Il4Il5Snai1
Anti-Fibrotic
Bmp7HgfIfngIl10Il13ra2
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Extracellular Matrix (ECM) Structural Constituents
Col1a2Col3a1
Extracellular Matrix (ECM) Remodeling Enzymes
LoxMmp1aMmp13Mmp14Mmp2Mmp3Mmp8Mmp9PlatPlauPlgSerpina1aSerpine1Serpinh1Timp1Timp2Timp3Timp4
Cell Adhesion Molecules
Itga1Itga2Itga3ItgavItgb1Itgb3Itgb5Itgb6Itgb8
Inflammatory Cytokines & Chemokines
Ccl11Ccl12Ccl3Ccr2Cxcr4IfngIl10Il13Il13ra2Il1aIl1bIl4Il5IlkTnf
Growth Factors
AgtCcn2Edn1EgfHgfPdgfaPdgfbVegfa
Signal Transduction
TGFβ Superfamily Members
Bmp7Cav1DcnEngGrem1InhbeLtbp1Smad2Smad3Smad4Smad6Smad7Tgfb1Tgfb2Tgfb3Tgfbr1Tgfbr2Tgif1Thbs1Thbs2
Transcription Factors
CebpbJunMycNfkb1Sp1Stat1Stat6
Epithelial-to-Mesenchymal Transition (EMT)
Akt1Bmp7Col1a2Col3a1ItgavItgb1Mmp2Mmp3Mmp9Serpine1Smad2Snai1Tgfb1Tgfb2Tgfb3Timp1
Other Fibrosis Genes
Bcl2Fasl