Target List
Necrosis
Regulation of Necrosis
FASFASLGRIPK1SLC25A4TNF
TNF-Induced Necrosis
ATP6V1G2CYLDDPYSL4EIF5BFOXI1GALNT5TMEM57GRB2LOC704611BMFDENND4ALOC712324HSPBAP1CCDC103MAGPARP2PVRRAB25DEFB1SPATA2SYCP2TXNL4B
Other Necrosis Genes
ARCA9CD40H2AFXRIPK1LOC708606RIPK3LOC721111MPGMGEA5PARP1SP1TMEM123
Potential Necrosis Genes
RIPK1 Interactors
RIPK3NFKB1RIPK2
RIPK3 Interactors
GLUD1GLULRIPK1PYGL
PARP1 Interactors
CAPN1CAPN2CAPN3CAPN7LOC698077LOC699341CAPN6
Death Domain Receptors
FASTNFRSF1ATNFRSF10A
Death Receptor Signaling
BIRC3CASP8AP2CYLDFAF1FEM1BNGFRAP1LOC698160LRDDIKBKGTNFSF15RIPK1LOC708606LOC711681MADDMYD88NGFRPARP1TNFRSF14TNFRSF17TNFRSF18TNFRSF19TNFRSF1BTNFRSF25TNFRSF4TNFRSF8TRAF5
Apoptosis
Pro-Apoptotic
AIFM1BNIP3LCASP8AP2FAF1FASFEM1BNGFRAP1FASLGLOC698160LRDDIKBKGBMFRIPK1LOC708606MADDRIPK3BAXLOC100426120NGFRRIPK2TNFRSF10ATNFRSF25TNFRSF8TNFSF10TRAF5
Anti-Apoptotic
BIRC3FASRIPK1LOC711681MYD88NFKB1NGFRRIPK2TNFTNFRSF1ATNFRSF1BTNFRSF4TRAF5
TNF-Induced Apoptosis
ATP6V1G2CYLDSPATA2SYCP2
Oxidative Stress
AIFM1GLUD1CYBBLOC696748NOX1NOX4
Mitochondrial Genes
AIFM1BNIP3LGLUD1GLULCYBBLOC696748RIPK1BAXSLC25A4