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GeneGlobe ID: JHS-004Z | Cat. No.: | QIAseq RNA Fusion XP Panels

RNA Fusion XP Lymphoma Panel

Kit containing ALL reagents (except indexes) for fusion and gene expression profiling by digital RNAseq

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Product Specification

Target List

Acute Lymphoblastic Lymphomas
CREBBPKMT2AMLLT10MYCP2RY8PRDM16STIL
Anaplastic Large Cell Lymphomas
ADGRG7ALKATICCLTCMSNMYCNPM1TFGTPM3TPM4ALKCDKN2ADNMT3ANRASSTAT3
Angioimmunoblastic T Cell Lymphomas
CD28CTLA4FIP1L1PDGFRAALKAPCARID1AASXL1ATMBRAFCDKN2ACREBBPCTNNB1DNMT3AEZH2FBXW7IDH2JAK1JAK3KITKMT2DKRASMED12PLCG1RHOASTAT3WT1XPO1ZFHX3
Burkitt Lymphomas
BCL6MYCPBX1TCF3APCARID1AATMCD79BCDKN2ACREBBPFBXW7HLA-AID3KRASMYCMYD88NRASPAX5PIK3CAPIK3R1PTENRHOASRSF2
Diffuse Large B Cell Lymphomas (DLBCL)
ALKBCL11ABCL6CCND3CIITACLTCIGLL5MAPK13MYCNPM1PIM1RELSQSTM1TBL1XR1TOMM40TP63ALKAMER1APCARID1AASXL1ATMB2MBCL2BCORBRAFBTKCD79BCDKN2ACNOT3CREBBPCTNNB1CXCR4DNMT3AEZH2FBXW7HLA-AID3IDH2IRS4JAK1JAK3KITKMT2DKRASMAP2K1MED12MSNMYCMYD88NCOR1NFKBIENOTCH2NRASNSD2PAX5PIK3CAPIK3R1PLCG1POT1PPM1DPTENRGS7RHOASF3B1SMOSRSF2STAT3STAT5BSTAT6TERTTRRAPWT1XPO1ZFHX3ZNF479
Follicular Lymphomas
AFF3BCL2BCL6CIITAMYCTBL1XR1TP63AMER1ARID1AATMB2MBCL2BCORBRAFBTKCD79BCDKN2ACREBBPCXCR4DNMT3AEZH2FBXW7ID3IDH2KMT2DMAP2K1MED12MYD88NOTCH2NRASPIK3R1PPM1DPTENRGS7RHOASRSF2STAT6ZMYM3
Hodgkin Lymphomas
ALKCIITAJAK2NPM1SEC31AARID1AASXL1B2MBCORCDKN2ADNMT3AEZH2NFKBIENRASPAX5PIK3R1PPM1DSF3B1
Inflammatory Myofibroblastic Tumors
ALKDCTN1
Lymphoblastic Lymphomas
BCRETV6FGFR1NOTCH1PBX1
Lymphoblastic T Cell Lymphomas
BCRETV6FGFR1FIP1L1LYNPDGFRA
Mantle Cell Lymphomas
CCND3MYCARID1AASXL1ATMB2MBCORBRAFBTKCDKN2ACREBBPDNMT3AIDH2KMT2DKRASMED12NCOR1NFKBIENOTCH2NRASNSD2PAX5POT1PPM1DPTENSTAT3TERTZFHX3
Mediastinal Large B Cell Lymphomas (MLBL)
CIITAPDCD1LG2
Mediastinal Large B-Cell Lymphomas
CIITAPDCD1LG2
Mucosa-Associated Lymphoid Tissue (MALT) Lymphomas
BCL6BIRC3CCND3MALT1MYCMYD88NOTCH2
Peripheral T Cell Lymphomas
ALKETV6FGFR3ITKMYO1FNPM1S100A7SYKTBL1XR1THAP4TP63VAV1ALKARID1AASXL1ATMCDKN2ACTNNB1DNMT3AIDH2IRS4KITKMT2DKRASMAP2K1MSNNRASPLCG1PTENRGS7RHOASTAT3STAT5BTRRAPXPO1ZFHX3ZNF479
Precursor T Cell Lymphoblastic Lymphomas
ABL1JAK2NUP214PCM1SETCTNNB1FBXW7NRASWT1
T Cell Lymphomas
ATXN2LFGFR1JAK2
Other Lymphomas
ALKATXN2LBCL6BIRC3CBFBCCND1CCND3CDK6CHIC2CLTCDEKDUSP22EIF4A1JAK2KMT2AMALT1MKL1MLF1MLLT10NFKB2NPM1PRDM16
Commercial Control Samples
ALKBAIAP2L1BRAFCCDC6CD74EGFREML4ERGETV6FGFR3KIF5BLMNAMETNCOA4NTRK1NTRK3PAX8PPARGRETROS1SEPT14SLC34A2SLC45A3TACC3TFGTMPRSS2TPM3
Checkpoint Molecules
Inhibitory on Tumor Cells​
CD200CD274CD274CD48CD80CD86ITGAVITGB3LGALS9MICAMICBPDCD1LG2TNFRSF14VSIR
Stimulatory on Tumor Cells​
CD40CD40LGCD48CD70CD86ICOSLGTNFRSF9TNFSF14TNFSF4TNFSF9
Inhibitory on T Cells​
BTLACD160CD200R1CD244CD274CD274CD28CTLA4HAVCR2KLRC1LAG3LILRB1LILRB3PDCD1PDCD1VSIR
Stimulatory on T Cells​
CD244CD27CD28CD40CD40LGICOSTNFRSF14TNFRSF18TNFRSF4TNFRSF9TNFSF14TNFSF9
T Cell Receptor Genes​
CD247CD3DCD3ECD3GTRACTRGC2
Major Histocompatibility Complex I Genes​
B2MHLA-AHLA-BHLA-CHLA-EHLA-FHLA-GHLA-HMR1
Major Histocompatibility Complex II Genes​
CD74HLA-DMAHLA-DMBHLA-DOAHLA-DOBHLA-DPA1HLA-DPB1HLA-DQA1HLA-DQA2HLA-DQB1HLA-DQB2HLA-DRAHLA-DRB1HLA-DRB5IFI30
Other Checkpoint Molecules​
ADORA2ABTNL2CD160CD276CD44CD52CD8AHHLA2IDO1IDO1IDO2KIR3DL1KLRD1LAIR1MS4A1NRP1TIGITTMIGD2TNFRSF25TNFRSF8TNFSF15VTCN1
Checkpoint Blockade Therapy Biomarkers
BTLACD274CD274CD80CD8ACSF2CXCL11HAVCR2HLA-DRAHLA-DRB1HLA-DRB5ICOSIFNGLAG3PDCD1PDCD1PDCD1LG2
Immuno Regulatory Gene Signature
ERBB2FASIL5RAINHBATNFRSF8TNFSF4TNFSF9
Immuno Stimulatory Gene Signature
CD160CD19CD200CD27CD44CTLA4HLA-AIL12RB2IL17AKITTNFRSF17
Immuno Suppressive Gene Signature
CD274CD274CD276HAVCR2PDCD1LG2TGFB1
Upregulated in Cancer Vaccination Response
CCL5CD3DCD86CD8ACXCL10CXCL9GBP1ICOSIRF1KLRD1PSMB9STAT1
Immune Cell Markers
CD8 T Cells​
CD8ACD8BFLT3LGGZMMPRF1
Th1 Cells​
CCL4CD38CD70CSF2CTLA4DPP4IFNGIL12RB2LTASTAT4TBX21
Th17 Cells​
IL17AIL17RARORC
Th2 Cells​
CXCR6GATA3IL26LAIR2MAFPMCHSMAD2STAT6
Follicular Helper T Cells​
BCL6CXCL13MAFPDCD1PDCD1
Other T Helper Cell Markers​
ANP32BBATFCD28ICOSNUP107
Regulatory T Cells​
FOXP3
Gamma Delta T Cells​
CD160FEZ1TRGC1
Central Memory T Cells​
ATMDOCK9FYB1NEFLREPS1TXKUSP9Y
Effector Memory T Cells​
AKT3CCR2EWSR1IL15RALTKNFATC4
Other T Cell Markers​
CD2CD247CD3DCD3ECD3GCD6IL2RBTNFRSF25TRACTRGC2
Myeloid Derived Suppressor Cells​
TGFB1
Cytotoxic Lymphocytes​
CD3ECD3GCD8ACD8BEOMESGZMAGZMBIFNGKLRC1KLRD1NKG7TBX21
Natural Killer Cells​
BCL2CD160FOXJ1FUT5GTF3C1GZMBIL21RKIR3DL1MPPED1NCR1PLA2G6RRADZNF205
Activated Dendritic Cells​
CCL1EBI3LAMP3OAS3
Immature Dendritic Cells​
CD1ACD1BCD1EF13A1SYT17
Myeloid Dendritic Cells​
CD1ACD1BCD1E
Plasmacytoid Dendritic Cells​
IL3RA
Other Dendritic Cell Markers​
CCL13CCL17CCL22CD209HSD11B1
Macrophages​
APOECCL7CD68CHIT1CXCL5MARCOMSR1
Neutrophils​
CSF3RFPR2MME
Eosinophils​
CCR3IL5RAPTGDR2SMPD3THBS1
Mast Cells​
CMA1CTSGKITMS4A2PRG2TPSAB1
B Cells​
BANK1BLKCD19CD79ACR2HLA-DOBHLA-DQA1MS4A1PAX5TNFRSF17
Antigen Presenting Cells​
CMKLR1
Regulatory T Cell Gene Signature
CD274CD274JAK1PDCD1LG2TIGITTNFRSF18TNFRSF4TNFRSF8TNFRSF9
T Cell Trafficking & Infiltration into Tumors
Stimulates T Cell Trafficking & Infiltration into Tumors​
CCL5CX3CL1CXCL10CXCL9ITGB2SELL
Other T Cell Trafficking & Infiltration into Tumors Genes​
CCL17CCL4CCR3CCR6CD274CD274CD44CSF2CXCL11CXCL13FOXP3IFNGITGA4ITGB7LTAPDCD1PDCD1PDCD1LG2PTENTNFRSF25TNFSF14
T Cell Exhaustion
Upregulated in T Cell Exhaustion​
CCL5CD200CD27CD69CTLA4CXCL10CXCL13GBP1HLA-DMAHLA-DQA1ICOSIFI16IFNGITGAVTAP1TIGITTNFRSF9
Downregulated in T Cell Exhaustion​
TNFRSF25
T Cell Exhaustion Transcriptional Nodes​
BATFTBX21
Responsiveness or Response Biomarkers
Enhanced Expression in Responsive Versus Nonresponsive Cancers​
APPCAPZBCCL4CCL5CD8ACSNK1ECTLA4CXCL10CXCL11CXCL9EBI3EHD1GBA2GZMBHLA-DQA1IDO1IDO1IFNGINHBAIRF2NKG7ODF2PHKG2PPIFPRF1SERPINA3SHMT2SIGMAR1SMAD3TIA1
Suppressed Expression in Responsive Versus Nonresponsive Cancers​
ACTG1BNIP3LCX3CL1FOXN3IFI27JAK1LTA4HNAIPOPTNPRRC2BPTENRBL2TXK
Differentially Expressed in Responsive Versus Nonresponsive Cancers​
ADAM28AKNAAOAHARHGAP9CACNA2D2CARD11CARD16CD109CLEC11ACORO1ACORO1BCXCR4FLT3FMNL1HIVEP1HIVEP2IFI44LIFITM1IGHA1IGHMIGSF6IKZF1ITPKALSM4LST1MAP3K14NFAM1NFKBIL1PLA2G2DPOU2AF1PTPRCAPSERPINB9SH3BP5SYTL1TMC8TNFRSF13BTNFRSF19ZFYVE9
Expression Correlates with Positive Objective Response Rates​
CD274CD274CD276CTLA4HAVCR2IDO1IDO1LAG3PDCD1LG2VTCN1
Upregulated during Treatment​
CD8ACTLA4CXCL10EOMESGZMAGZMBICOSIFNGPRF1
Regulated during Treatment​
IRF1
Pre-Treatment Response Prediction
Predicts Enhanced Response​
ADAM17MYCRHOCTIMP1
Other Pre-Treatment Response Predictors​
CDK2CDKN2ALARGE1NAB2NRAS
Cancer Cell Killing
Inhibits Cancer Cell Killing​
BTLACD274CD274CD80HAVCR2IDO1IDO1IDO2LAG3MICAMICBPDCD1PDCD1TGFB1VSIRVTCN1
Stimulates Cancer Cell Killing​
IFNG
Antigen Processing & Presentation
Proteasome​
PSMB10PSMB9
Proteases​
IFI30
Endoplasmic Reticulum & Lysosomal Transport​
TAP1TAP2TAPBPL
Major Histocompatibility Complex I Genes​
B2MHLA-AHLA-BHLA-CHLA-EHLA-FHLA-GHLA-HMR1
Major Histocompatibility Complex II Genes​
CD74HLA-DMAHLA-DQA1HLA-DRAHLA-DRB1HLA-DRB5IFI30
Immune Cell Receptors & Co-Receptors​
CD8ACD8BKIR3DL1KLRC1KLRD1
Stimulates Antigen Presentation​
CD40CD40LG
Interferon Gamma Response
Cytokines & Chemokines​
CCL5IL15RASTAT1
Major Histocompatibility Complex I Genes​
B2MHLA-AHLA-BHLA-CHLA-EHLA-FHLA-GHLA-H
Major Histocompatibility Complex II Genes​
HLA-DMAHLA-DQA1HLA-DRAHLA-DRB1HLA-DRB5IFI30
RNA Degradation​
OAS3
Transcription Factors​
IRF1IRF2
Other Interferon Gamma Response Genes​
CD44GBP1
Cytosolic DNA-Sensing Pathway
Cytokines & Interferons​
CCL4CCL5CXCL10
Expression Altered due to Genetic Alterations
BCL10BCL2BCL3BCL6BCL9CCND1CCND2CCND3CD44CDK6ERVW-1FCGR2BFCRL4FOXP1GPR34IRF4KDSRMALT1MTCP1MUC1MYCNBEAP1NFKB2PAX5PRDM16
AIDS-Related Lymphomas
EZH2
B Cell Lymphomas
ARID1AATMB2MBCL2BCORBRAFCD79BCDKN2ACREBBPCTNNB1CXCR4DNMT3AEZH2JAK3KITKMT2DMAP2K1MYD88PIK3CAPPM1DPTENRHOASTAT3
Small Lymphocytic Lymphomas
ALKAPCARID1AASXL1ATMBCL2BCORBRAFBTKCD79BCDKN2ACNOT3CREBBPCXCR4DNMT3AFBXW7GNASIRS4JAK1JAK3KITKMT2DKRASMAP2K1MED12MSNMYCMYD88NCOR1NFKBIENOTCH2NRASPAX5PIK3CAPIK3R1PLCG1POT1PPM1DPTENRGS7SF3B1STAT5BSTAT6TERTTRRAPXPO1ZFHX3ZMYM3ZNF479
Cutaneous T Cell Lymphomas
KRASPTEN
Diffuse Red Pulp Small B Cell Lymphomas
MYD88NOTCH2
Enteropathy-Type T Cell Lymphomas
STAT5B
Gamma-Delta T Cell Lymphomas
STAT3STAT5B
Hepatosplenic T Cell Lymphomas
STAT3STAT5B
Lymphoplasmacytic Lymphomas
ARID1ABTKCD79BCXCR4DNMT3AMYD88
Marginal Zone Lymphomas
AMER1ARID1AASXL1ATMBRAFCD79BCREBBPCXCR4DNMT3AEZH2FBXW7GNASJAK3KITKMT2DMAP2K1MYD88NFKBIENOTCH2PIK3R1RHOASRSF2TRRAPXPO1
Mycosis Fungoides (Sezary Syndrome)
AMER1ARID1AATMBCORCDKN2ADNMT3AJAK1JAK3KMT2DKRASNCOR1NRASPIK3CAPLCG1POT1PTENSTAT3STAT5B
NK-T Cell Lymphomas
ALKAMER1APCARID1AASXL1ATMB2MBCORBRAFCTNNB1DNMT3AEZH2FBXW7HLA-AJAK1JAK3KITKMT2DKRASMED12NCOR1NOTCH2NRASPOT1RGS7RHOASMOSTAT3STAT5BWT1XPO1ZFHX3
Primary Central Nervous System Lymphomas
B2MBCL2CD79BCDKN2ACXCR4DNMT3AHLA-AJAK3KITKRASMYD88NOTCH2POT1STAT3STAT5BTERTTRRAPWT1
Primary Effusion Lymphomas
CDKN2APTEN

Product Resources

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Resources

Brochures & Guides (2)
Massively Parallel Sequencing Solutions for Human Identity
PDF (2MB)

Next-generation sequencing using QIAGEN’s QIAseq – a powerful tool for human identification


The QIAseq advantage – interactive product profile
PDF (2MB)
State-of-the-art technologies to fast-track and streamline NGS workflows
Application Notes (2)
Noninvasive prenatal paternity testing by means of SNP-based targeted sequencing barcoded with Unique Molecular Indices
PDF (435KB)

The use of UMIs as part of a QIAseq targeted sequencing panel

QIAseq SPE technology for Illumina: Redefining amplicon sequencing
PDF (238KB)
Safety Data Sheets (2)
Safety Data Sheets
Download Safety Data Sheets for QIAGEN product components.
QIAseq 8-UDI Kit Set D (48)
Kit Handbooks (1)
QIAseq RNA Fusion XP Panel Handbook
PDF (3MB)
Template Files (1)
QIAseq RNA Fusion XP All-in-One Tool
SOFTWARE (884KB)
Certificates of Analysis (1)
Certificates of Analysis
Introducing the RNA Fusion XP Lymphoma Panel, a cutting-edge addition to our QIAseq RNA Fusion XP Panels lineup, specifically designed for {{application}} applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the RNA Fusion XP Lymphoma Panel facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting {{application}}, or any other sophisticated analyses, this product from our QIAseq RNA Fusion XP Panels collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with RNA Fusion XP Lymphoma Panel and elevate your work to new heights.
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