Target List
Glucocorticoid Receptor & Cotranscription Factors
ATF4CEBPACEBPBCREB1CREB3CREB3L4NR3C1 (GRL)POU2F1POU2F2STAT5ASTAT5B
Glucocorticoid Receptor Target Genes
Glucose & Fatty Acid Metabolism
ASPHGDPD1GLULGOT1H6PDPDP1
Cytokines & Chemokines
EDN1IL10IL1RNIL6IL6RTNF
Growth Factors
ANGPTL4CCN2
Extracellular Matrix (ECM) Molecules
COL4A2HAS2LOX
Cytoskeleton Regulators
PLEKHF1RHOBRHOJSNTA1
Endocytosis & Exocytosis
ANXA4EHD3MERTKPLEKHF1
Cell Surface Receptors
CALCRGHRHRPDGFRBVLDLR
Channels & Transporters
AQP1SLC10A6SLC19A2SLC22A5
Signal Transduction
BMPERDIRAS2DUSP1 (PTPN16)NFKBIA (IκBα, MAD3)PIK3R1 (p85-ALPHA)PLD1RASA3RGS2SESN1SGK1SPHK1TNFUSP2
Stress Responses
BCL6DDIT4 (REDD1)PDCD7SESN1SGK1
Transcription Factors
ARID5BCEBPBFOSL2KLF13KLF9NFKBIA (IκBα, MAD3)TBL1XR1TNFAIP3TSC22D3VDRZFP36ZHX3
Circadian Rhythm
PER1PER2
RNA Processing
ADARB1AFF1HNRNPLL
Protein Folding & Trafficking
FKBP5LOX
Metallothioneins
MT1EMT2A
Nucleotide Metabolism
AK2AMPD3XDH
Other Glucocorticoid Receptor Target Genes
CYB561ERRFI1SPSB1USP54ZNF281
Up-Regulated in Adipose & Muscle Tissue
ADARB1AFF1AMPD3ANXA4ARID5BASPHBMPERDDIT4 (REDD1)DUSP1 (PTPN16)EHD3ERRFI1FKBP5GDPD1GLULH6PDHNRNPLLKLF13LOXMERTKPDP1PER1PER2PIK3R1 (p85-ALPHA)PLD1PLEKHF1RASA3RGS2RHOJSESN1SGK1SLC10A6SNTA1SPHK1SPSB1TBL1XR1TSC22D3USP2USP54VDRVLDLRXDHZFP36ZHX3
Up-Regulated in Muscle Tissue
CCN2CEBPBCOL4A2CYB561DIRAS2EDN1KLF9
Up-Regulated in Adipose Tissue
ANGPTL4BCL6FOSL2NFKBIA (IκBα, MAD3)RHOBSLC19A2SLC22A5TNFAIP3
Down-Regulated in Adipose Tissue
AK2DIRAS2HAS2PDGFRB