Target List
Toll-Like Receptor (TLR) Signaling
Toll-Like Receptors & Chaperones
CTSBCTSLCTSSTLR3TLR7TLR8TLR9
Signaling Downstream of Toll-Like Receptors
CHUK (IKKα)FOSIKBKB (IKKβ)IRAK1IRF3IRF5IRF7JUNMAP2K1MAP2K3 (MEK3)MAP3K7 (TAK1)MAPK1 (ERK2)MAPK14 (p38ALPHA)MAPK3 (ERK1)MAPK8 (JNK1)MYD88NFKB1NFKBIA (IκBα, MAD3)RELARIPK1SPP1TBK1TICAM1 (TRIF)TNFTRAF3TRAF6
Toll-Like Receptor Signaling Responsive Genes
CCL3 (MIP-1A)CCL5 (RANTES)CD40 (TNFRSF5)CD80CD86CXCL10 (INP10)CXCL11 (I-TAC, IP-9)CXCL9 (MIG)IFNA1IFNA2IFNB1IL12AIL12BIL15IL1BIL6
NOD-Like Receptor (NLR) Signaling
Receptors & Signaling Molecules
AIM2
NOD-Like Receptors & Signaling Molecules
CARD9CASP1 (ICE)HSP90AA1MEFVNLRP3NOD2OAS2PSTPIP1PYCARD (TMS1, ASC)PYDC1 (POP1)SUGT1
NOD-Like Receptor Signaling Responsive Genes
IL1BIL18
RIG-I-Like Receptor Signaling
Receptors & Chaperones
CYLD
RIG-I-Like Receptors & Chaperones
TKFCDDX58DHX58IFIH1ISG15TRIM25
Signaling Downstream of RIG-I-Like Receptors
ATG5AZI2CASP10 (MCH4)CASP8 (FLICE)CHUK (IKKα)DDX3XFADDIKBKB (IKKβ)IRF3IRF7MAP3K1 (MEKK1)MAP3K7 (TAK1)MAPK14 (p38ALPHA)MAPK8 (JNK1)MAVSNFKB1NFKBIA (IκBα, MAD3)PIN1RELARIPK1TBK1TNFTRADDTRAF3TRAF6
RIG-I-Like Receptor Signaling Responsive Genes
CXCL10 (INP10)IFNA1IFNA2IFNB1IL12AIL12BCXCL8 (IL8)
Type I Interferon Signaling & Response
Type I Interferon Signaling
IFNA1IFNA2IFNAR1IFNB1STAT1
Interferon Responsive Genes
APOBEC3GIL15ISG15MX1TLR3