Target List
Skeletal Development
Cartilage Condensation
Bmp1Bmpr1b (Alk6)Col2a1Sox9
Ossification
Acvr1 (Alk2)Ahsg (QuantiNova Symbol: AABR07034632.1)BglapBmp1Bmp2Bmp3Bmp4Bmp5Bmp6Bmp7Bmpr1a (Alk3)Bmpr1b (Alk6)Bmpr2Cdh11ChrdCol1a1Col2a1Csf1 (Mcsf)CtskDlx5Fgf2 (bFGF)Fgfr2Gdf10 (Bmp3b)Gli1Igf1Igf1rIhhLOC103689974 (Tnfsf11)Mmp2Mmp8Mmp9NogRunx2Smad1Smad3SostSox9Sp7Spp1Tgfb1Tgfb2Tgfb3Twist1
Osteoclast Differentiation
BglapCsf1 (Mcsf)LOC103689974 (Tnfsf11)LOC103694380 (Tnf)
Osteoblast Differentiation
Acvr1 (Alk2)BglapBmp2Bmp4Bmp6Bmp7Bmpr1a (Alk3)Bmpr1b (Alk6)Bmpr2ChrdCol1a1Dlx5Fgf2 (bFGF)Fgfr2Gdf10 (Bmp3b)Gli1Igf1IhhNogRunx2Smad1Smad3Sp7Spp1Twist1
Other Skeletal Development Genes
AlplCompFgfr1Tgfbr1 (Alk5)Tgfbr2Tgfbr3
Bone Mineral Metabolism
Bone Mineralization
Acvr1 (Alk2)Ahsg (QuantiNova Symbol: AABR07034632.1)BglapBmp2Bmp4Bmp6Bmp7Bmpr1a (Alk3)Bmpr1b (Alk6)Bmpr2Fgfr2Igf1Smad3Sox9Tgfb1Tgfb3Twist1
Calcium Ion Binding & Homeostasis
Anxa5BglapCdh11CompEgfFgf2 (bFGF)ItgavItgb1Mmp2Mmp8Tgfb1Vdr
Extracellular Matrix (ECM) Molecules
Collagens
Col10a1Col14a1Col1a1Col1a2Col2a1Col3a1Col4a1Col5a1Col6a1
Extracellular Matrix (ECM) Protease Inhibitors
Ahsg (QuantiNova Symbol: AABR07034632.1)Serpinh1 (Hsp47)
Extracellular Matrix (ECM) Proteases
CtskMmp10Mmp2Mmp8Mmp9Phex
Other Extracellular Matrix (ECM) Molecules
AlplBgnFlt1 (Vegfr1)
Cell Adhesion Molecules
Cell-Cell Adhesion
Bmp1Bmpr1b (Alk6)Cdh11Col14a1Col2a1Icam1IhhItgb1LOC103689974 (Tnfsf11)LOC103694380 (Tnf)Sox9Tgfb1Vcam1
Cell-Extracellular Matrix (ECM) Adhesion
Cd36 (QuantiNova Symbol: RGD1565355)Col3a1Csf1 (Mcsf)Itga2Itga3ItgadItgavItgb1Smad3
Other Cell Adhesion Molecules
BglapCol5a1CompFn1LOC103694380 (Tnf)
Growth Factors
Csf2 (Gm-csf)Csf2 (Gm-csf)Csf2 (Gm-csf)Csf3 (Gcsf)EgfFgf1Fgf2 (bFGF)Gdf10 (Bmp3b)Igf1PdgfaVegfaVegfb
Transcription Factors
Gli1Nfkb1Runx2Smad1Smad2Smad3Smad4Smad5Sox9Twist1