Target List
Toll-Like Receptor (TLR) Signaling
Receptors & Chaperones
CTSBCTSVCTSSTLR2TLR3TLR7TLR8TLR9
Signaling Downstream of Toll-Like Receptors
BCL2JUNCHUK (IKKα)CSF2 (GM-CSF)FOSIKBKBIRAK1IRF3IRF5IRF7MAP2K1 (MEK1)MAP3K7 (TAK1)MAP3K8MAPK1 (ERK2)MAPK1 (ERK2)MAPK14 (p38ALPHA)MAPK14 (p38ALPHA)MAPK3 (ERK1)MAPK3 (ERK1)MAPK8MYD88NFKB1NFKBIA (IκBα, MAD3)PELI1RELARIPK1SPP1TBK1TICAM2TNFTRAF3TRAF6
Toll-Like Receptor Signaling Responsive Genes
CCL3L1 (CCL3)CCL4 (MIP-1B)CCL5 (RANTES)CD40CD80CD86CXCL10 (INP10)CXCL11 (I-TAC, IP-9)CXCR4CXCL9 (MIG)IFNB1IL12AIL12BIL15IL1BIL23AIL6
NOD-Like Receptor Signaling
Receptors & Signaling Molecules
CASP1HSP90AA1MEFVNLRP3NOD2OAS2PSTPIP1LOC100522011SUGT1
NOD-Like Receptor Signaling Responsive Genes
IL1BIL18
RIG-I-Like Receptor Signaling
Receptors & Chaperones
TKFCDDX58DHX58IFIH1ISG15 (G1P2)CYLDLOC100737114
Signaling Downstream of RIG-I-Like Receptors
ATG5AZI2BCL2CASP10CASP8 (FLICE)CHUK (IKKα)DDX3XIKBKBIRF3IRF7MAP3K1 (MEKK1)MAP3K7 (TAK1)MAP3K8MAPK14 (p38ALPHA)MAPK14 (p38ALPHA)MAPK8MAVSNFKB1NFKBIA (IκBα, MAD3)PIN1RELARIPK1TBK1TNFLOC100620340TRAF3TRAF6
RIG-I-Like Receptor Signaling Responsive Genes
CXCL10 (INP10)IFNB1IL12AIL12BCXCL8
Type I Interferon Signaling & Response
Type I Interferon Signaling
IFNAR1IFNB1STAT1
Interferon Responsive Genes
CSF2 (GM-CSF)CXCR4IL15IL23AISG15 (G1P2)MX1TLR3