Target List
Apoptosis
BCL2BIRC5
PI3 Kinases & Phosphatases
MTORPIK3C2APIK3C3 (VPS34)PIK3CA (p110-alpha)
Growth Factors & Receptors
EGFR (ERBB1)ERBB2 (HER-2, NEU)ERBB3ERBB4FLT1 (VEGFR1)FLT4 (VEGFR2)IGF1IGF1RIGF2KDR (VEGFR3)KIT (CD117)PDGFRAPDGFRBVEGFD (VEGFD)
Drug Metabolism
ABCC1 (MRP1)GSTP1PTGS2 (COX2)TXNTXNRD1
G-Protein Signaling
RHOARHOB
Hormone Receptors
ESR1 (ERα)ESR2 (ERβ)PGR
Heat Shock Proteins
HSP90AA1HSP90B1
Receptor Tyrosine Kinase Signaling
AKT1AKT2GRB2
Cathepsins
CTSBCTSDCTSLCTSS
Cell Cycle
CDC25ACDK1CDK2CDK4CDK5CDK7CDK8CDK9MDM2MDM4TERT
Topoisomerases, Type II
TOP2ATOP2B
Transcription Factors
ATF2 (CREB2)HIF1AIRF5NFKB1TP53 (p53)
Protein Kinases
AURKAAURKBAURKCPLK1PLK2PLK3PLK4PRKCAPRKCBPRKCDPRKCE
RAS Signaling
HRASKRASNRAS
Histone Deacetylases
HDAC1HDAC11HDAC2HDAC3HDAC4HDAC6HDAC7HDAC8
Poly ADP-Ribose Polymerases
PARP1 (ADPRT1)PARP2PARP4TNKS (TIN1)
Structural Proteins
NTN3