Target List
TGFβ Superfamily Ligands
Activins
INHAINHBAINHBB
Bone Morphogenetic Proteins
AMHBMP1BMP2BMP3BMP4BMP5BMP6BMP7GDF2GDF3GDF5GDF6GDF7
Nodal
NODAL
TGFβ Family Members
TGFB1TGFB2TGFB3
Inhibitors & Cofactors of TGFβ Signaling
BAMBICHRDDCNFSTLEFTY1LTBP1LTBP2NOGTGFBITGFBRAP1TGIF1THBS1
TGFβ Superfamily Receptors
Activin Receptors
ACVR1ACVR2AACVRL1
Bone Morphogenetic Protein Receptors
AMHR2BMPR1ABMPR1BBMPR2
TGFβ Receptors
TGFBR1TGFBR2TGFBR3
Transcription Factors & Regulators
DLX2FOSGSCHIPK2ID1JUNJUNBMYCRUNX1SMAD1SMAD2SMAD3SMAD4SMAD5SMAD7SOX4STAT1TGFB1I1TSC22D1
SMAD Target Genes
TGFβ / Activin-Responsive
ATF4CDKN1ACDKN1BCDKN2BCOL1A1COL1A2DCNEMP1FOSGADD45BGSCHERPUD1IFRD1IGF1IGFBP3IL6JUNJUNBMYCPDGFBSERPINE1TGFB1I1TGFBITGIF1TNFSF10TSC22D1
Bone Morphogenetic Protein Responsive
BGLAPDLX2ID1ID2JUNBSOX4STAT1
Molecules Regulating TGFβ Superfamily Signaling
BAMBIBMPERCDKN2BCHRDENGFSTHIPK2MECOMNOGPLAURUNX1SMURF1
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Cell Adhesion Molecules
BGLAPENGTGFB1I1TGFBI
Extracellular Matrix (ECM) Structural Constituents
BGLAPCOL1A1COL1A2LTBP1LTBP2TGFBI
Cellular & Developmental Processes
Apoptosis
CDKN1ACDKN1BHIPK2IGFBP3INHAINHBASTAT1TGFB1
Embryonic Development
BMP4INHBAMECOMSMAD3SMURF1
Muscle Development
DCNIGF1SMAD3
Neurogenesis
DLX2INHAINHBANOG
Reproduction
AMHAMHR2FSTINHAINHBAINHBB
Skeletal Development
BGLAPBMP1BMP2BMP3BMP4BMP5BMP6BMP7BMPR2CHRDCOL1A1COL1A2IGF1INHAINHBANOG