Target List
Acute Rejection - Innate Immunity
Pattern Recognition Receptors (PRRs)
TLR3TLR4TLR9
Cytokines
CCL11CCL2CCL4CCL5CSF2CXCL10CXCL8IFNGIL10IL12AIL13IL16IL1BIL2IL2RAIL3IL32IL4IL5IL6TNF
Other Innate Immunity Genes
ADAM17C3CASP1CASP3CASP8CCR2CCR3CD14CD28CD8AFASFASLGFCGR1AGZMAGZMBMS4A1NFKB1NOS2PRF1PSMB9STAT1STAT6TAP1TNFAIP3TNFSF10
Acute Rejection - Adaptive Immunity
Th1 Markers & Immune Response
CCR5CCR7CD80CTLA4CXCR3IFNGSTAT4
Th2 Markers & Immune Response
CD86IL10IL13IL4IL5IL6
T-Cell Activation
CD80CD86ICAM1IFNG
Cytokines
CCL2CCL4CCL5CSF2CXCL10IFNGIL10IL13IL4IL5IL6TNF
Leukocyte Recruitment
CD40CD40LGICAM1THBS1VCAM1
Chronic Rejection
Pro-Fibrotic
CCL3CCN2IL13IL4IL5
Anti-Fibrotic
BMP7COL1A2IFNGIL10THBS2
Cell Adhesion Molecules
ICAM1ITGA2ITGAEITGAMVCAM1
Cellular Infiltration
BMP7CCR2CD44COL1A2CX3CR1CXCL11CXCL9CXCR4MMP1MMP2MMP7MMP9PECAM1TGFB1TGFB2TGFB3THBS2TIMP1VEGFA