Target List
Genomic Instability
Bub1bMrpl43PolrmtTfamTfb1mTfb2mZmpste24
Telomere Attrition
Pot1Rap1aTerf1Terf2Tinf2Tpp1
Mitochondrial Dysfunction
Mrpl43Ndufb11PolrmtSirt3Sirt6TfamTfb1mTfb2m
Proteostasis
Arl6ip6Bub1bFoxo1Hsf1Jakmip3Rnf144bTxnipVps13c
Laminopathies
LmnaLmnb1Lmnb2Zmpste24
Neurodegeneration & Synaptic Transmission
Calb1GfapMbpScn2bSnap23
Epigenetic Alterations
Arid1aSirt3Sirt6
DNA Binding
Arid1aElp3Ep300Fbxl16Zbtb10Zfp9Zfr
RNA Binding
Elavl1Lsm5Zfr
Inflammatory Response
Angel2Anxa3Anxa5C1qaC1qbC1qcC1sC3C3ar1C4aC4bC5ar1Ccr1Cd14Cd163CfhCfhr1Cx3cl1Cxcl16Fcer1gFcgbpFcgr1aFcgr2aFcgr2bGfapLtfLyzl1MbpPanx1S100a8S100a9Tlr2Tlr4Tmem135Tmem33Tollip
Apoptosis
Casp1CluEp300Pdcd6Tollip
Cellular Senescence
Cdkn1cVwa5aWrn
Cell Cycle
Bub1bCdkn1c
Cytoskeleton Regulators
Col1a1Eml1
Oxidative Stress
Ep300
Transcriptional Regulation
Arid1aEp300Foxo1Hsf1Phf3Smad2