Target List
Pro-Fibrotic
ACTA2AGTCCL11CCL2CCL3CCN2GREM1IL13IL13RA2IL4IL5SNAI1
Anti-Fibrotic
BMP7HGFIFNGIL10IL13RA2
Extracellular Matrix (ECM) & Cell Adhesion Molecules
Extracellular Matrix (ECM) Structural Constituents
COL1A2COL3A1
Extracellular Matrix (ECM) Remodeling Enzymes
LOXMMP1MMP13MMP14MMP2MMP3MMP8MMP9PLATPLAUPLGSERPINA1SERPINE1SERPINH1TIMP1TIMP2TIMP3TIMP4
Cell Adhesion Molecules
ITGA1ITGA2ITGA3ITGAVITGB1ITGB3ITGB5ITGB6ITGB8
Inflammatory Cytokines & Chemokines
CCL11CCL2CCL3CCR2CXCR4IFNGIL10IL13IL13RA2IL1AIL1BIL4IL5ILKTNF
Growth Factors
AGTCCN2EDN1EGFHGFPDGFAPDGFBVEGFA
Signal Transduction
TGFβ Superfamily Members
BMP7CAV1DCNENGGREM1INHBELTBP1SMAD2SMAD3SMAD4SMAD6SMAD7TGFB1TGFB2TGFB3TGFBR1TGFBR2TGIF1THBS1THBS2
Transcription Factors
CEBPBJUNMYCNFKB1SP1STAT1STAT6
Epithelial-to-Mesenchymal Transition (EMT)
AKT1BMP7COL1A2COL3A1ILKITGAVITGB1MMP2MMP3MMP9SERPINE1SMAD2SNAI1TGFB1TGFB2TGFB3TIMP1
Other Fibrosis Genes
BCL2FASLG