Target List
Toll-Like Receptor (TLR) Signaling
Toll-Like Receptors & Cofactors
CD14LY96TLR1TLR2TLR4TLR5TLR6TLR9
MYD88-Dependent
FADDIRAK1IRAK3IRF5IRF7MAP3K7MYD88TIRAPTLR1TLR2TLR4TLR5TLR6TLR9TOLLIPTRAF6
TICAM1 (TRIF)-Dependent (MYD88-Independent) Signaling
IRF5IRF7MAP3K7RIPK1TICAM1TICAM2TLR4TRAF6
Other Toll-Like Receptor Signaling Genes
AKT1CASP8LBPPIK3CARAC1
NOD-Like Receptor (NLR) Signaling
NOD-Like Receptors
NAIPNLRC4NLRP1NLRP3NOD1NOD2
Inflammasomes
CASP1NAIPNLRC4NLRP1NLRP3PYCARD
Regulation of NOD-like Receptor (NLR) Signaling
BIRC3CARD6CARD9CASP8HSP90AA1MEFVPSTPIP1RIPK2SUGT1TNFXIAP
Other Bacterial Pattern Recognition Receptors (PRRs)
APCSCRPDMBT1ZBP1
Signaling Downstream of Antibacterial Responses
NFκB Signaling
CHUKIKBKBNFKB1NFKBIARELATNFRSF1A
ERK1 / ERK2 Signaling
JUNMAP2K1MAPK1MAPK3
JNK / p38 Signaling
JUNMAP2K3MAP2K4MAPK14MAPK8
Apoptosis
AKT1BIRC3CARD6CARD9CASP1CASP8CD14FADDIFNB1IKBKBIL12AIL12BIL1BIL6IRAK1JUNMAP3K7MAPK1MAPK8MPONFKB1NFKBIAPIK3CAPYCARDRAC1RIPK1RIPK2TNFTNFRSF1ATRAF6
Inflammatory Response
AKT1APCSCCL3CCL5CD14CRPCXCL1CXCL2IL1BIL6CXCL8LBPLY96LYZMEFVMYD88NFKB1NLRC4NLRP3NOD1RAC1RELARIPK2SLC11A1TICAM2TIRAPTLR1TLR2TLR4TLR5TLR6TLR9TNFTNFRSF1ATOLLIP
Cytokines & Chemokines
CCL3CCL5CXCL1CXCL2IFNA1IFNB1IL12AIL12BIL18IL1BIL6CXCL8
Antimicrobial Peptides
BPICAMPCTSGLCN2LTFLYZMPOPRTN3SLPI