Target List
ATM / ATR Signaling
ATMATRATRIPBARD1BRCA1CDC25ACHEK1CHEK2CSNK2A2FANCD2H2AFXHUS1MDC1PARP1RAD1RAD17RAD50RAD9ARBBP8RNF168RNF8SMC1ATOPBP1TP53
DNA Damage & Repair
Nucleotide Excision Repair (NER)
CDK7DDB1DDB2ERCC1ERCC2LIG1NTHL1OGG1PCNAPNKPRPA1SIRT1TP53XPAXPC
Base Excision Repair (BER)
APEX1FEN1LIG1MBD4MPGNTHL1OGG1PARP1PCNATP53UNGXRCC1
Mismatch Repair (MMR)
ABL1EXO1MLH1MLH3MSH2MSH3PCNAPMS1PMS2TP73
Double-Strand Break (DSB) Repair
ATMBLMBRCA1CHEK1H2AFXHUS1LIG1MDC1MLH1MRE11NBNPRKDCRAD50RAD51RPA1TP53BP1XRCC2XRCC6
Other DNA Repair Genes
ATRATRIPATRXBARD1BRIP1CHEK2CIB1CRY1FANCAFANCD2FANCGGADD45AGADD45GRAD1RAD17RAD18RAD21RAD51BRAD9ARBBP8REV1RNF168RNF8SMC1ASUMO1TOPBP1XRCC3
Apoptosis
ABL1ATMBARD1BAXBBC3BRCA1CDKN1ACHEK2CIB1CSNK2A2PPP1R15APRKDCRAD21RAD9ASIRT1TP53TP73
Cell Cycle
ATMATRATRIPCDC25ACDC25CCDK7CDKN1ACHEK1CHEK2DDIT3MAPK12MCPH1MDC1PPM1DPPP1R15ATP53TP73