Target List
Upregulated in Immunotoxicity
ABCA1ABCG1ADH1CAHSGAPOA5APOFC9F2FABP1GSTA3HPXHRGMARC1NR5A2PON1SERPINA3VPREB1
Downregulated in Immunotoxicity
APOL3APOL4BTNL10BZRAP1CCNB2CDR2CRIM1CTSEGPR17GYPAHMGCS1ISG20KLF1KLF2LYZMKI67SLC7A11SNCATRIM10
Immune Response
AHSGANGC9CCR5CEBPBCTSEHPXF2FN1IFI6JCHAINIGSF6ISG20KLF2LAT2LYZPAWRSERPINA3SNCATHBS1TLR4VPREB1
Inflammatory Response
AHSGAPOL3CCR5CEBPBF2FN1SERPINA3SPP1TLR4
Drug Metabolism
ADH1CALDH8A1BZRAP1CYP3A5GSTA3MARC1MT1FNQO1PON1
Drug Transporters
ABCA1ABCG1SLC25A13SLC31A1SLC7A11
Glucocorticoid Signaling
AK4CEBPBVLDLR
Heat Shock Response
HSPA1BHSPA5
Oxidative Stress
HPXKLF2MT1FNQO1PON1SLC7A11SNCASRXN1
Unfolded Protein Response
CEBPBCHAC1HSPA1BHSPA5TM6SF1VLDLR
Cell Cycle
CCNB2CCNG2FBXO32FBXO38KLHL24MKI67
Channels & Transporters
ABCA1ABCG1ATP2B1CHAC1KCNQ1SLC25A13SLC31A1SLC7A11
Cytoskeletal Regulators
ANGGEMIN5GYPAHRGMYH3PAWR
Cytokine & Chemokine Receptors
ACKR3CCR5CRIM1GPR17TLR4
Extracellular Matrix (ECM) & Cell Adhesion Molecules
FEZ1FN1GPNMBHRGSERPINA3SPP1THBS1
G-Protein Coupled Receptor Signaling
ARRDC3CCR5ACKR3GPR17GPR18
Lipoprotein Signaling & Cholesterol Metabolism
ABCA1ABCG1ALDH8A1APOA5APOFAPOL3APOL4HMGCS1VLDLRVPREB1
Transcription Factors
ATF3CEBPBID1ID2KLF1KLF2NR5A2PAWRTRIM10ZDHHC14
Other Immunotoxicity Genes
BTNL10C7orf50CDR2FABP1METAP2NEU4PSD3SNX25VMP1