Target List
Immune & Inflammatory Responses
Immunostimulatory Factors
IfngIl2Il12aIl12bIl15Tnf
Immunosuppressive Factors
Cd274 (Pdl1)Cd274 (Pdl1)Csf2 (GMCSF)Ctla4Cxcl12Cxcl5 (ENA-78, LIX)Ido1 (Ido)Ido1 (Ido)Il10Il13Il4Il5MifNos2 (iNos)Pdcd1 (PD-1)Pdcd1 (PD-1)Ptgs2 (Cox2)Tgfb1Vegfa
Pro-inflammatory Genes
Ccl2 (MCP-1)Ccl2 (MCP-1)Ccl2 (MCP-1)Ccl20 (Mip-3a)IfngIl1aIl1bIl2Il6Il12aIl12bIl17aIl22Il23aPtgs2 (Cox2)Tlr4TnfVegfa
Anti-inflammatory Genes
Il4Il10Il13Tgfb1
Enzymatic Modulators of Inflammation & Immunity
Aicda (Aid)Aicda (Aid)GzmaGzmbIdo1 (Ido)Ido1 (Ido)Nos2 (iNos)Ptgs2 (Cox2)
Antigen Presentation
H2-D1H2-K1
Chemokines
Ccl2 (MCP-1)Ccl2 (MCP-1)Ccl2 (MCP-1)Ccl4 (Mip-1b)Ccl5 (Rantes)Ccl20 (Mip-3a)Ccl22 (Mdc)Ccl28Cxcl1 (Gro1)Cxcl2 (Gro2)Cxcl5 (ENA-78, LIX)Cxcl9 (Mig)Cxcl10 (Inp10)Cxcl11 (Itac, Ip9)Cxcl11 (Itac, Ip9)Cxcl11 (Itac, Ip9)Cxcl12
Interleukins
Il1aIl1bIl2Il4Il5Il6Il10Il12aIl12bIl13Il15Il17aIl22Il23a
Chemokine & Interleukin Receptors
Ackr3Ccr1Ccr2Ccr4Ccr5Ccr7Ccr9Ccr10Cxcr1Cxcr2Cxcr3Cxcr4Cxcr5Il1r1
Other Cytokines
Kitl (Scf)MifSpp1TnfTnfsf10 (Trail)
Growth Factors & Receptors
Csf1 (Mcsf)Csf2 (GMCSF)Csf3 (Gcsf)EgfEgfrIgf1Tgfb1Vegfa
Signal Transduction
Interferon Signaling
Gbp2bIfngIl6Irf1
Interferon-Responsive Genes
Ccl2 (MCP-1)Ccl2 (MCP-1)Ccl2 (MCP-1)Ccl5 (Rantes)Cxcl9 (Mig)Cxcl10 (Inp10)Gbp2bIrf1Myd88Stat1Tlr3Tnfsf10 (Trail)
NFκB Targets
Bcl2l1 (Bcl-XL)Bcl2l1 (Bcl-XL)Bcl2l1 (Bcl-XL)Ccl2 (MCP-1)Ccl2 (MCP-1)Ccl2 (MCP-1)Ccl5 (Rantes)Csf1 (Mcsf)Csf2 (GMCSF)Csf3 (Gcsf)IfngTnf
STAT Targets
Ccl2 (MCP-1)Ccl2 (MCP-1)Ccl2 (MCP-1)Ccl4 (Mip-1b)Ccl5 (Rantes)Csf1 (Mcsf)Csf2 (GMCSF)Csf3 (Gcsf)Cxcl9 (Mig)Cxcl10 (Inp10)Cxcl11 (Itac, Ip9)Cxcl11 (Itac, Ip9)Cxcl11 (Itac, Ip9)Cxcl12Il1bIl6Il10Il17aIl23aMyc
Toll-Like Receptor Signaling
Myd88Tlr2Tlr3Tlr4Tlr7Tlr9
Transcription Factors
Foxp3Hif1aIrf1MycNfkb1Stat1Stat3Trp53 (p53)
Apoptosis
Pro-Apoptotic
FaslTnfTnfsf10 (Trail)Trp53 (p53)
Anti-Apoptotic
Bcl2Bcl2l1 (Bcl-XL)Bcl2l1 (Bcl-XL)Bcl2l1 (Bcl-XL)MycStat3