Target List
Up-Regulated in Neurotoxicity
Apoptosis
Bag4BikCasp7Cdkn1a (Cip1, Waf1)CideaCidebCraddDapk1FasFaslgGch1LOC100909750 (Abl1)Sod2Tnfrsf10b (QuantiNova Symbol: AABR07018323.1)Tnfrsf11b (Opg)Tp53 (p53)Traf4Ywhae
Neuron Development
Casp7Drp2EregHephIl10Mmp9Plp1Sod2Tp53 (p53)Ywhae
Metabolism (Regulation & Mechanism)
Arg2Arrb1Atf4Cdkn1a (Cip1, Waf1)CideaDdit3 (Gadd153, Chop)Dynll1EregGalGucy1a1Hsp90aa1Il10LOC100909750 (Abl1)Nfkb1Pou1f1 (Pit-1)PygbRasd1Slc16a3Sod2Tnfrsf10b (QuantiNova Symbol: AABR07018323.1)Tp53 (p53)Traf2Usp7Ywhae
Nitric Oxide Response
Arg1Arg2Dynll1Gch1Gucy1a1LOC100361087 (Nos1ap)NosipNostrinRasd1Slc16a3
Signal Transduction
Arrb1Cd8bCdkn1a (Cip1, Waf1)CideaCidebDapk1Ddit3 (Gadd153, Chop)FaslgGpr37Gucy1a1Hspa5 (Grp78)Il10LOC100909750 (Abl1)Rasd1Tnfrsf10b (QuantiNova Symbol: AABR07018323.1)Tp53 (p53)Traf2Ywhae
Ion Transporters
Camk2dClcn5ClcnkbHephSfxn5Trpm1Trpm4
Other Genes Up-Regulated in Nephrotoxicity
Angptl4Pappa1Pdia4
Down-Regulated in Neurotoxicity
Apoptosis
Lta (Tnfb)Nol3Tnfrsf25 (Dr3)Xiap
Neuron Development
BdnfKit (Cd117)Lefty2 (Ebaf)Lta (Tnfb)Notch4Sema3b
Metabolism (Regulation & Mechanism)
BdnfCamk2aCcnd1Cdo1Drd2Eif2ak3GalcGrin1GsrHtr1aKit (Cd117)Notch4Prim2Tph1TxnipTyrp1
Signal Transduction
Birc2 (c-IAP2)Ccnd1Drd2Eif2ak3GsnHtr1aKit (Cd117)Tacr1
Ion Transporters
Drd2Grin1
Other Genes Down-Regulated in Neurotoxicity
Col12a1Egln3Htr3aNup50