Target List
Necrosis
Regulation of Necrosis
FasFaslgLOC103694380 (Tnf)Ripk1Slc25a4
TNF-Induced Necrosis
Atp6v1g2BmfCommd4CyldDefb1Dennd4aDpysl4Foxi1Galnt5Grb2Hspbap1Kcnip1Maco1MagOlr1583Parp2PvrRab25RGD1311517Spata2Sycp2Txnl4b
Other Necrosis Genes
Cd40FaddOgaParp1 (Adprt1)PpiaRipk1Ripk3Sp1Tmem123
Potential Necrosis Genes
RIPK1 Interactors
Cetn1FusNfkb1Ripk2Ripk3
RIPK3 Interactors
Glud1GlulPhtf2PyglRipk1
PARP1 Interactors
Capn1Capn2Capn3Capn5Capn6Capn7Capns1 (QuantiNova Symbol: LOC100912380)Ppid
Death Domain Receptors
FasTnfrsf10b (QuantiNova Symbol: AABR07018323.1)Tnfrsf1a (Tnfr1)
Death Receptor Signaling
Bex3BidBirc3 (c-IAP1)Casp8ap2CyldFaddFaf1Fem1bIkbkgLOC100911519 (Pidd1)MaddMyd88NgfNgfrParp1 (Adprt1)Ripk1Tnfrsf14Tnfrsf17Tnfrsf1bTnfrsf25 (Dr3)Tnfrsf4 (Ox40)Tnfrsf8Tnfsf15TraddTraf2
Apoptosis
Pro-Apoptotic
Aifm1BaxBex3BidBmfBnip3lCasp8ap2FaddFaf1FasFaslgFem1bIkbkgLOC100911519 (Pidd1)LOC103694380 (Tnf)MaddNgfrRipk1Ripk2Ripk3Tnfrsf10b (QuantiNova Symbol: AABR07018323.1)Tnfrsf25 (Dr3)Tnfrsf8Tnfsf10 (Trail)TraddTraf2
Anti-Apoptotic
ArBirc3 (c-IAP1)Bnip3lCar9FasLOC103694380 (Tnf)Myd88Nfkb1NgfNgfrRipk1Ripk2Tnfrsf1a (Tnfr1)Tnfrsf1bTnfrsf4 (Ox40)Traf2
TNF-Induced Apoptosis
Atp6v1g2CyldSpata2Sycp2
Oxidative Stress
Aifm1CybaCybbGlud1Nox1Nox4
Mitochondrial Genes
Aifm1BaxBidBnip3lCybaCybbGlud1GlulPpidRipk1Slc25a4