Target List
TNF Superfamily Members
Induction of Apoptosis
FaslLta (Tnfb)Tnfsf10 (Trail)Tnfsf14Tnfsf8
Caspase Activation
Tnfsf15
Caspase Inhibition
Tnfsf14
Anti-Apoptotic
Cd40lgTnfTnfsf18
Other Apoptosis Genes
Cd70Tnfsf9
Inflammatory Response
Cd40lgTnf
NFκB Signaling
FaslTnfTnfsf10 (Trail)Tnfsf14Tnfsf15
Other TNF Superfamily Members
LtbPglyrp1Tnfsf11 (Rankl)Tnfsf12 (Apo3l)Tnfsf13Tnfsf13bTnfsf4 (Ox40l)Psmg2
TNF Receptor Superfamily Members
Induction of Apoptosis
FasTnfrsf10b (Dr5)Tnfrsf19Tnfrsf25 (Dr3)Cd27Tnfrsf9Tradd
Caspase Activation
Tnfrsf10b (Dr5)
Caspase Inhibition
Cd27
Anti-Apoptotic
FasTnfrsf18Cd27
Other Apoptosis Genes
Cd40LtbrNgfrTnfrsf11b (Opg)Tnfrsf12aTnfrsf14Tnfrsf1a (Tnfr1)Tnfrsf1bTnfrsf21
Inflammatory Response
Cd40Tnfrsf1a (Tnfr1)
NFκB Signaling
Cd40Eda2rLtbrTnfrsf10b (Dr5)Tnfrsf1a (Tnfr1)Cd27Tradd
JNK / p38 Signaling
Eda2rTnfrsf19Cd27
Other TNF Receptor Superfamily Members
Tnfrsf11a (Rank)Tnfrsf13bTnfrsf13cTnfrsf17ReltTnfrsf4 (Ox40)Tnfrsf8
TNFR1 Signaling
Induction of Apoptosis
Casp3CraddFaddTradd
Caspases
Casp2Casp3Casp8 (Flice)
Anti-Apoptotic
Bag4Casp2Tnf
Other Apoptosis Genes
DffaPak1Tnfrsf1a (Tnfr1)Traf2
Inflammatory Response
TnfTnfrsf1a (Tnfr1)
NFκB Signaling
Casp8 (Flice)FaddTnfTnfrsf1a (Tnfr1)Tradd
JNK / p38 Signaling
Map2k4 (Mkk4, Jnkk1)Mapk8 (Jnk1)Pak1
Transcriptional Regulation
JunParp1Rb1TnfTnfrsf1a (Tnfr1)
Other TNFR1 Signaling Genes
ArhgdibCadLmnaLmnb1Lmnb2Map3k1 (Mekk1)Map3k7 (Tak1)Pak2PrkdcSptan1
TNFR2 Signaling
Induction of Apoptosis
IkbkgLta (Tnfb)Traf3
Anti-Apoptotic
Nfkb1Tnfaip3
Other Apoptosis Genes
Nfkbia (Iκbα, Mad3)Tnfrsf1bTraf1Traf2
Inflammatory Response
Nfkb1
NFκB Signaling
Chuk (IKBKA)Ikbkb (IKKbeta)IkbkgNfkbia (Iκbα, Mad3)TankTnfaip3
Transcriptional Regulation
Ikbkb (IKKbeta)IkbkgNfkb1Nfkbia (Iκbα, Mad3)
Other TNFR2 Signaling Genes
Dusp1 (Ptpn16)Map3k1 (Mekk1)Map3k14
Death Receptor Signaling
Apaf1Bcl2BidCflar (Casper)Cycs