Target List
Autophagy Machinery Components
Autophagic Vacuole Formation
Ambra1 (Nyw1)Atg12Atg16l1Atg4aAtg4bAtg4cAtg4dAtg5Atg9aAtg9bBecn1GabarapGabarapl1Gabarapl2Irgm1Map1lc3aMap1lc3bRgs19Ulk1Wipi1
Vacuole Targeting
Atg4aAtg4bAtg4cAtg4dGabarap
Protein Transport
Atg10Atg16l1Atg16l2Atg3Atg4aAtg4bAtg4cAtg4dAtg7Atg9aGabarapGabarapl2Rab24
Autophagosome-Lysosome Linkage
Dram1GabarapLamp1Npc1
Ubiquitination
Atg3Atg7Hdac6
Proteases
Atg4aAtg4bAtg4cAtg4d
Regulation of Autophagy
Co-Regulators of Autophagy & Apoptosis
Dram1Akt1AppAtg12Atg5BadBak1BaxBcl2Bcl2l1 (Bcl-XL)Bcl2l1 (Bcl-XL)Bcl2l1 (Bcl-XL)Becn1BidBnip3Casp3Casp8 (Flice)Cdkn1b (p27Kip1)Cdkn2a (p16INK4a)Cln3CtsbCxcr4Dapk1Eif2ak3FaddFasHdac1HttIfngIgf1Ins2Mapk8 (Jnk1)MtorNfkb1Pik3cgPrkaa1 (Ampk)PtenSncaSqstm1Tgfb1Tgm2TnfTnfsf10 (Trail)Trp53 (p53)
Co-Regulators of Autophagy & the Cell Cycle
BaxCdkn1b (p27Kip1)Cdkn2a (p16INK4a)IfngPtenRb1Tgfb1Trp53 (p53)
Autophagy Induction by Intracellular Pathogens
Eif2ak3IfngLamp1
Autophagy in Response to Other Intracellular Signals
CtsdCtssDram2Eif4g1Esr1 (Erα)GaaHgsMapk14 (p38alpha)Pik3c3 (Vps34)Pik3r4Rps6kb1Tmem74Ulk2Uvrag
Chaperone-Mediated Autophagy
Hsp90aa1Hspa8