Target List
Mutated in Non-Motile Cilia Diseases
AHI1ALMS1ARL13BARL6BBS1BBS2BBS4BBS7CC2D2ACep290GLIS2HNF1BINVSIQCB1MKKSMKS1NEK8NPHP1NPHP3PKD1PKD2PKHD1RPGRIP1LTMEM67 (MKS3)TTC8
Intraflagellar Transport (IFT)
DYNC2LI1IFT172IFT20IFT74IFT80IFT88KIF3AKIF3B
Cilium Morphogenesis
ALMS1ARL6BBS1BBS2BBS4BBS7IFT172IFT88MKKSOFD1PKHD1RPGRIP1LVANGL2WWTR1
Signal Transduction
Hedgehog Signaling
BTRC (bTrCP)FUZGLI1GLI2GLI3GSK3BIHHINTULRP2PTCH1RAB23SHHSMOSUFU
cAMP Signaling
ADCY3ADCY7AVPR2HTR6PKD2SSTR3
mTOR Signaling
AKT1CDC42GSK3BIGF1INSMAPK1 (ERK2)MTORPIK3CA (p110-alpha)PRKCARHOATP53 (p53)TSC1TSC2
Planar Cell Polarity (PCP)
DVL1FAT4FJX1FUZFZD1INTURHOAROCK2VANGL2WNT9B
WNT Signaling
AXIN2INVS
PDGFRA / Integrin Signaling
ITGB1PDGFRA
BRAF / MEK / ERK
FOSKRASMAP2K1MAPK1 (ERK2)MOSPRKCAPTPN5
Cell Cycle
AKT1BBS4CCND1CDK5RAP2CDKN1A (p21CIP1, WAF1)IGF1INSMAP2K1PKD1PKD2TP53 (p53)