Target List
Induction of Apoptosis
Death Domain Receptors
CRADDFADDTNFTNFRSF10B
DNA Damage & Repair
ABL1CIDEACIDEBTP53TP73
Extracellular Apoptotic Signals
CFLARDAPK1TNFRSF25
Other Pro-Apoptotic Genes
BADBAK1BAXBCL10BCL2L11BIDBIKBNIP3BNIP3LCASP1CASP10CASP14CASP2CASP3CASP4CASP6CASP8CD27CD70CYCSDFFADIABLOFASFASLGGADD45AHRKLTANOD1PYCARDTNFRSF10ATNFRSF9TNFSF10TNFSF8TP53BP2TRADDTRAF3
Anti-Apoptotic
AKT1BAG1BAG3BAXBCL2BCL2A1BCL2L1BCL2L1BCL2L1BCL2L10BCL2L2BFARBIRC3BIRC5BIRC6BNIP2BNIP3BNIP3LBRAFCD27CD40LGCFLARDAPK1FASHRKIGF1RIL10MCL1NAIPNFKB1NOL3RIPK2TNFXIAP
Regulation of Apoptosis
Negative Regulation of Apoptosis
BAG1BAG3BCL10BCL2BCL2A1BCL2L1BCL2L1BCL2L1BCL2L10BCL2L2BFARBIRC2BIRC3BIRC6BNIP2BNIP3BNIP3LBRAFCASP3CD27CD40LGCFLARCIDEADAPK1DFFAFASIGF1RMCL1NAIPNOL3TP53TP73XIAP
Positive Regulation of Apoptosis
ABL1AKT1BADBAK1BAXBCL2L11BIDBIKBNIP3BNIP3LCASP1CASP10CASP14CASP2CASP4CASP6CASP8CD40CD70CIDEBCRADDFADDFASLGHRKLTALTBRNOD1PYCARDRIPK2TNFTNFRSF10ATNFRSF10BTNFRSF25TNFRSF9TNFSF10TNFSF8TP53TP53BP2TRADDTRAF2TRAF3
Death Domain Receptors
CRADDDAPK1FADDTNFRSF10ATNFRSF10BTNFRSF11BTNFRSF1ATNFRSF1BTNFRSF21TNFRSF25TRADD
Caspases & Regulators
Caspases
CASP1CASP10CASP14CASP2CASP3CASP4CASP5CASP6CASP7CASP8CASP9CFLARCRADDPYCARD
Caspase Activation
AIFM1APAF1BAXBCL2L10CASP1CASP9NOD1PYCARDTNFRSF10ATNFRSF10BTP53
Caspase Inhibition
CD27XIAP