Target List
p53 Activation
ATMATRBBC3BRCA1CDKN1ACDKN2ACHEK1CHEK2FOXO3GMLMDM2MSH2SIRT1TP63TP73
p53 Regulators & Interactors
CDKN2ADNMT1HDAC1KAT2BMDM2MDM4SIRT1TADA3TP53AIP1TP53BP2TP63TP73
p53 Targets
Apoptosis
APAF1BAXBBC3BTG2CASP9EGFREI24ESR1FASPRKCATNFTNFRSF10BTP53TP53AIP1TP73
Cell Cycle
CCNG1CDC25ACDC25CCDKN1AE2F1E2F3GMLMDM2MYCPPM1DRB1RPRMSESN2SIAH1
DNA Damage & Repair
BRCA1BTG2EGFRGADD45APCNAPTTG1
Angiogenesis
ADGRB1IL6PTEN
Responses Downstream of p53 Signaling
Apoptosis
APAF1BCL2BCL2A1BIDBIRC5CASP2CASP9CRADDFADDFASLGIGF1RMCL1NF1NFKB1PIDD1RELATNFRSF10DTRAF2WT1
Cell Cycle
CCNB1CCNE1CCNG1CCNHCDK1CDK4PRC1TSC1
DNA Damage & Repair
BRCA2MLH1XRCC5
Transcription Factors & Regulators
BRCA2EGR1JUNMYOD1NFKB1RELASTAT1
Other Responses Downstream of p53 Signaling
HK2KRAS