Target List
Inflammasomes
AIM2
AIM2CASP1PYCARD
IPAF
CASP1NAIPNLRC4PYCARD
NLRP1
CASP1CASP5NLRP1
NLRP3
CASP1NLRP3PYCARD
Negative Regulation of Inflammasomes
BCL2BCL2L1BCL2L1BCL2L1CARD18CD40LGCTSBHSP90AA1HSP90AB1HSP90B1MEFVPSTPIP1PYDC1SUGT1TNFTNFSF11TNFSF14TNFSF4
Signaling Downstream of Inflammasomes
IFNGIL12AIL12BIL18IL1BIL33IRAK1IRF1MYD88P2RX7PANX1PTGS2MOKRIPK2TIRAPTXNIP
NOD-Like Receptors
NOD-Like Receptors
CIITANAIPNLRC4NLRC5NLRP1NLRP12NLRP3NLRP4NLRP5NLRP6NLRP9NLRX1NOD1NOD2
Signaling Downstream of NOD-Like Receptors
BIRC2BIRC3CARD6CASP8CCL2CCL5CCL7CFLARCHUKCXCL1CXCL2FADDIFNB1IKBKBIKBKGIL6IRF1IRF2MAP3K7MAPK1MAPK11MAPK12MAPK13MAPK3MAPK8MAPK9NFKB1NFKBIANFKBIBPEA15RELARIPK2SUGT1TAB1TAB2TNFTRAF6XIAP
Pro-Inflammatory Caspases
CASP1CASP5