Target List
Insulin Signaling
AKT3IGF1IGF1RIKBKBINSRIRS1IRS2MAP2K1MAPK3MAPK9MTORPDE3BPIK3CAPIK3R1PPARGC1APTPN1RPS6KB1SLC2A4SOCS3SREBF1
Non-Insulin Dependent Diabetes Mellitus
ADIPOQHK2IKBKBINSRIRS1IRS2MAPK3MAPK9MTORPDX1PIK3CAPIK3R1SLC2A4SOCS3TNF
Adipokine Signaling
Adipokines
ADIPOQIL6LEPNAMPTRETNSERPINE1TNF
Receptors & Transporters
ADIPOR1ADIPOR2CD36LEPRSLC2A4TNFRSF1ATNFRSF1B
Signaling Downstream of Adipokines
AKT3CHUKIKBKBIRS1IRS2JAK2MAPK9MTORNFKBIAPPARAPPARGC1ARELASOCS3STAT3
Innate Immunity
CASP1CHUKIKBKBIRS1IRS2NLRP3NFKBIAPYCARDRELATLR4
Inflammation
ALOX5CASP1CCL2CCR4CCR5CHUKCXCR4IFNGIKBKBIL1BIL23RIL6CXCL8LTA4HNLRP3OLR1PYCARDRELATNFTNFRSF1ATNFRSF1B
Apoptosis
PPARGSERPINE1TNFCASP1IKBKBIRS2MAPK9NFKBIANLRP3PYCARDRELATNFRSF1AJAK2PIK3CASOCS3RPS6KB1TNFRSF1B
Metabolic Pathways
Carbohydrate Metabolism
CSHK2PCK1PDK2
Lipid Metabolism
ACACAACACBACSL1ACSL4APOECEBPACNBPFABP4FASNLEPRLIPELPLPPARAPPARGPPARGC1ASCDSREBF1SREBF2
Metabolite Transport
APOECD36FABP4RBP4SLC2A4SLC27A1UCP1VLDLR
Infiltrating Leukocyte Markers
Macrophages
CCR5CXCR4ADGRE1
Th1 Cells
CCR5CD3ECXCR3IL18R1
Th2 Cells
CCR4CD3ECRLF2IL1R1
Th17 Cells
CCR6CD3EIL23R