Target List
Oncogenes
BAXBCL2L1BCL2L1BCL2L1CASP8CDK4ELK1ETS1HGFJAK2JUNBJUNDKITKITLGKITLGMCL1METMOSMYBNFKBIANRASPIK3CAPMLPRKCARAF1RARARELROS1RUNX1SRCSTAT3ZHX2
Tumor Suppressor Genes
ATMBRCA1BRCA2CDH1CDKN2BCDKN3E2F1FHITFOXD3HIC1IGF2RMEN1MGMTMLH1NF1NF2RASSF1RUNX3S100A4SERPINB5SMAD4STK11TP73TSC1VHLWT1WWOXXRCC1
Both Oncogenic & Tumor Suppressor Properties
BCREGFERBB2ESR1FOSHRASJUNKRASMDM2MYCMYCNNFKB1PIK3C2ARB1RETSH3PXD2ATGFB1TNFTP53
Transcription Factors
ABL1BRCA1BRCA2CDKN2ACTNNB1E2F1ELK1ESR1ETS1FOSFOXD3HIC1JUNJUNBJUNDMDM2MEN1MYBMYCMYCNNF1NFKB1PMLRARARB1RELRUNX1RUNX3SMAD4STAT3TGFB1TNFTP53TP73TSC1VHLWT1ZHX2
Epithelial-to-Mesenchymal Transition (EMT)
BRCA2CDKN2BCTNNB1ERBB2HGFJAK2KITMCL1NF1RUNX3S100A4SMAD4TGFB1VHL
Angiogenesis
AKT1CTNNB1EGFERBB2NF1PMLRUNX1TGFB1
Apoptosis
BAXBCL2BCL2L1BCL2L1BCL2L1BRCA1CASP8E2F1MCL1MGMTTNFVHL
Cell Adhesion Molecules
APCCDH1CDKN2ACTNNB1KITLGKITLGNF1NF2TGFB1
Cell Cycle
ATMBRCA1BRCA2CCND1CDK4CDKN1ACDKN2ACDKN2BCDKN3E2F1HGFMEN1STK11TP53