Target List
Induction of Apoptosis
Death Domain Receptors
CraddFaddTnfTnfrsf10b
DNA Damage & Repair
CideaCidebTrp53Trp63Trp73
Extracellular Apoptotic Signals
CflarDapk1
Other Pro-Apoptotic Genes
BadBak1BaxBcl10Bcl2l11BidBnip3Bnip3lBokCasp1Casp12Casp14Casp2Casp3Casp4Casp6Casp8Cd70DffaDffbDiabloFasFaslMapk1Nod1PycardTnfsf10Trp53bp2Traf3
Anti-Apoptotic
Akt1Api5Atf5Bag1Bag3BaxBcl2Bcl2l1Bcl2l1Bcl2l1Bcl2l10Bcl2l2Birc3Birc5Bnip2Bnip3Bnip3lCd40lgCflarDad1Dapk1FasIgf1rIl10Lhx4Mcl1Naip1Naip2Nfkb1Nme5Nol3PolbPrdx2TnfTrp63Xiap
Regulation of Apoptosis
Negative Regulation of Apoptosis
Bag1Bag3Bcl10Bcl2Bcl2a1aBcl2l1Bcl2l1Bcl2l1Bcl2l10Bcl2l2Birc2Birc3Bnip2Bnip3Bnip3lCasp3Cd40lgCflarCideaDapk1DffaFasMcl1Nol3Trp53Trp73Xiap
Positive Regulation of Apoptosis
Abl1Akt1Anxa5BadBak1BaxBcl2l11BidBnip3Bnip3lCard10Casp1Casp14Casp2Casp4Casp6Casp8Cd40Cd70CidebCraddFaddFaslGadd45aLtbrNod1PycardTnfTnfrsf10bTnfsf10Tnfsf12Trp53Trp53bp2Traf1Traf2Traf3
Death Domain Receptors
CraddDapk1FaddNfkb1Ripk1Tnfrsf10bTnfrsf11bTnfrsf1a
Caspases & Regulators
Caspases
Casp1Casp12Casp14Casp2Casp3Casp4Casp6Casp7Casp8Casp9CflarCraddPycard
Caspase Activation
Aifm1Apaf1BaxBcl2l10Casp1Casp9Nod1PycardTnfrsf10bTrp53
Caspase Inhibition
Birc5Xiap