Target List
p53 Activation
AtmAtrBrca1Cdkn1aCdkn2aChek2Ep300Foxo3Mdm2Msh2Pmaip1Sirt1Tp63Tp73
p53 Regulators & Interactors
Cdkn2aDnmt1Hdac1Mdm2Mdm4Sirt1Tp53bp2Tp63Tp73
p53 Targets
Apoptosis
Apaf1BaxBtg2Casp9EgfrEsr1FasLOC103694380Pmaip1PrkcaSfnTnfrsf10bTp53Tp73Zmat3
Cell Cycle
Ccng1Cdc25aCdc25cCdkn1aE2f1E2f3Mdm2MycPpm1dRb1RprmSesn2
DNA Damage & Repair
Brca1Btg2EgfrGadd45aPcnaPttg1
Angiogenesis
Il6PtenSerpinb5
Responses Downstream of p53 Signaling
Apoptosis
Apaf1Bag1Bcl2Bcl3BidBirc5Bnip3BokCasp2Casp9Cul9Dapk1FaddFaslgIgf1rNf1Nfkb1RelaWt1
Cell Cycle
Ccnb1Ccne1Ccng1CcnhCdk1Cdk4Prc1
DNA Damage & Repair
Apex1BokBrca2Ercc1Lig4Mlh1Xrcc4Xrcc5
Transcription Factors & Regulators
Bcl3Brca2Egr1Hif1aJunMyod1Nfkb1RelaStat1
Other Responses Downstream of p53 Signaling
KrasStt3a