Target List
Toll-Like Receptors
Muc13Tlr1Tlr2Tlr3Tlr4Tlr5Tlr6Tlr7Tlr8Tlr9
Pathogen-Specific Responses
Bacterial Response
Ccl2Ccl2Ccl2Cd14FosHrasIl10Il12aIl1bIl6Irak1Hmgb1Hspa1aJunLtaLy86Ly96NfkbiaPglyrp1Ptgs2RelaRipk2Tlr2Tlr4Tlr6Tnfrsf1aTicam1
Viral Response
Eif2ak2Ifnb1IfngIl12aIl6Irf3RelaTbk1Tlr3Tlr7Tlr8TnfTicam1
Fungal / Parasitic Response
Clec4eHrasHspa1aTlr2Tirap
Toll-Like Receptor (TLR) Signaling
Negative Regulation of Toll-Like Receptor (TLR) Signaling
Tollip
TICAM1 (TRIF)-Dependent (MYD88-Independent) Signaling
Irf3Map3k7Nr2c2Peli1Tbk1Ticam2Tlr3Tlr4Traf6Ticam1
MYD88-Dependent Signaling
Irak1Irak2Map3k7Myd88Nr2c2TirapTlr1Tlr2Tlr4Tlr5Tlr6Tlr7Tlr8Tlr9Traf6
Signaling Downstream of Toll-Like Receptors
NFκB Signaling
BtkCasp8ChukFaddAgfg1IkbkbIl1r1Il10Il1bIrak1Irak2Irf3Ly96Map3k1Map3k7Nfkb1Nfkb2NfkbiaNfkbibNfkbil1NfrkbPparaRelRelaTnfTnfaip3Tnfrsf1aTraddUbe2nUbe2v1
JNK / p38 Signaling
Elk1FosIl1bJunMap2k3Map2k4Map3k1Map3k7Mapk8Mapk8ip3Mapk9Tnf
JAK / STAT Signaling
Ccl2Ccl2Ccl2Csf2IfngIl12aIl2Il6
Interferon Regulatory Factor (IRF) Signaling
Cxcl10Ifnb1IfngIrf1Irf3Tbk1
Cytokine Signaling
Ccl2Ccl2Ccl2CebpbCsf3Il1aIl1bIl1r1Il6Il6raIrak1Irak2RelaTnfTnfrsf1a
Regulation of Adaptive Immunity
Cd80Cd86Hspd1IfngIl10Il12aIl1bIl2Map3k7Traf6
Toll-Like Receptor Interacting Proteins & Adaptors
BtkCd14Hmgb1HrasHspa1aHspd1Ly86Ly96Mapk8ip3Myd88Peli1Pglyrp1Ripk2Ticam1Ticam2TirapTollip
Downstream Effectors of Toll-Like Receptor Signaling
Casp8Eif2ak2FaddIrak1Irak2Map3k7Nr2c2PparaTraf6Ube2nUbe2v1