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GeneGlobe ID: DHS-6600Z | Cat. No.: | QIAseq Targeted DNA Panels

QIAseq Targeted DNA Human Tumor Mutational Burden Panel

Kit containing ALL reagents (except indexes) for targeted DNA sequencing

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Product Specification

Target List

Oncogenes
ABL1AKT1AKT2ALKARBCL2BRAFCARD11CBLCDK4CRKLCRLF2 (TSLPR)CSF1RCTNNB1DNMT3AEGFR (ERBB1)ERBB2 (HER-2, NEU)EZH2FGFR2FGFR3FLT3FOXL2GATA2GNA11GNAQGNASH3-3AH3C2HRASIDH1IDH2IKBKEJAK1JAK2JAK3KIT (CD117)KRASMAP2K1MED12METMPLMYD88NFE2L2NRASPDGFRAPIK3CA (p110-alpha)PPP2R1APTPN11RELRETSF3B1SMOSPOPSRCTSHRU2AF1
Tumor Suppressor Genes
ACVR1BAMER1APCARID1AARID1BARID2ARID5BASXL1ASXL2ATMATRXAXIN1B2MBAP1BARD1BCORBRCA1BRCA2CDC73CDH1 (E-Cadherin)CDKN2A (P16INK4A)CEBPACICCREBBP (CBP)CYLDDAXXEP300FAT1FBXW7FLCNFOXP1FUBP1GATA1GATA3HNF1AKDM5CKDM6AKMT2CKMT2DMAP3K1 (MEKK1)MEN1MLH1NF1NF2NOTCH1NOTCH2NPM1PAX5PHF6PIK3R1 (p85-ALPHA)PRDM1PTCH1PTENRB1RNF43RUNX1 (AML1)SMAD2 (MADH2)SMAD4 (MADH4)SMARCA4SMARCB1SOCS1SOX9STAG2STK11 (LKB1)TET2TNFAIP3TP53 (p53)TSC1TSC2VHLWT1ZFHX3
Angiogenesis
AKT1AKT2AKT3CTNNB1ERBB2 (HER-2, NEU)FGFR2FLT1 (VEGFR1)FLT4 (VEGFR2)GATA2KDR (VEGFR3)NF1NOTCH1PIK3CA (p110-alpha)PTENPTGS2 (COX2)RUNX1 (AML1)TNFAIP3VEGFAVEGFD (VEGFD)VHL
Apoptosis
ABL1ABL2 (ARG)AKT1AKT2AKT3APCARAFAXIN1BCL2BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL2L1 (BCLXL)BCL6BRAFCASP8 (FLICE)CBLCDKN1A (p21CIP1, WAF1)CDKN2A (P16INK4A)CTNNA1CTNNB1CYLDDAXXFASFLT3FOXL2GATA1HGFHRASMAP2K4 (MKK4, JNKK1)MCL1MDM4MYCNNF1NPM1PIM1PRKCIPTENRAD21RAD50RAD51RAF1RB1RELSOX9STK11 (LKB1)TNFTNFAIP3TP73VHLWT1
Cell Adhesion Molecules
ABL1ABL2 (ARG)APCCDH1 (E-Cadherin)CTNNB1DDR2EGFR (ERBB1)EPCAMERBB2 (HER-2, NEU)FAT1GATA1JAK2KDR (VEGFR3)NF1NF2NOTCH1PDGFRAPTENPTGS2 (COX2)PTPN11RAC1RETRHOASRCTSC1
Cell Cycle
ABL1ABL2 (ARG)AKT1AKT2AKT3APCATRBLMBRD4CCND1CCND2CCND3CCNE1CDC27CDC73CDK12CDK4CDK6CDK8CDKN1A (p21CIP1, WAF1)CDKN1B (P27KIP1)CDKN2A (P16INK4A)CDKN2B (p15INK4b)CDKN2C (p18-INK4C)CHEK1CHEK2 (RAD53)CREBBP (CBP)CUX1CYLDFBXW7FGFR2HRASMYCNPM1PIM1PTENPTPRDRAD21RAD50RAD51RB1RHEBRHOASMARCA4SMARCB1SMC1ASMC3SOX2SOX9STAG2STK11 (LKB1)TNFAIP3TP53 (p53)TP53BP1TSC1WEE1XPO1ZFHX3
DNA Damage & Repair
ABL1ABL2 (ARG)APCATMATRATRXAXIN2BRCA1BRCA2BRIP1CDKN1A (p21CIP1, WAF1)CHEK1CHEK2 (RAD53)EP300EPCAMERCC1ERCC2 (XPD)ERCC3 (XPB)ERCC4ERCC5EXO1FANCAFANCCFANCD2FANCEFANCFFANCGGADD45AHERC1HMGB1HMGN1LIG1LIG3MCM2MCM3MCM4MCM5MCM6MCM7MDM2MEN1MLH1MLH3MRE11MSH2MSH3MSH4MSH5MSH6MTORMUTYHNBNNPM1PALB2PARP1 (ADPRT1)PCNAPIK3C2BPMS1PMS2POLBPOLD1POLD2POLD3POLD4POLEPOLE4PRKCGPRKCZPRKDCRAD17RAD18RAD21RAD50RAD51RAD51CRFC1RFC2RFC3RFC4RFC5RNASEH2ARPA1RPA2RPA3RPA4SETD2SIRT1SMC1ASMC3SSBP1STK11 (LKB1)TDGTP53 (p53)TP53BP1TP73TREX1TRRAPXRCC5
Epigenetics
ARID1AARID1BARID2ARID5BASXL1ASXL2ATRXAURKAAURKBBCORBCORL1BRD4CHD4CTCFDICER1DNMT3ADOT1LEEDEZH2FOXA1H3-3AH3C2IKZF1KAT6AKDM5AKDM5CKDM6AKMT2AKMT2CKMT2DNCOR1NSD1PBRM1PHF6PRDM1RARARUNX1T1SMARCA4SMARCB1SPOPSUZ12TET2TRRAP
Hypoxia Signaling
CREBBP (CBP)EP300NF1PDK1SMAD4 (MADH4)VHL
Immune Response
ALKB2MBTKCARD11CD274 (PD-L1)CD274 (PD-L1)CD276CD79ACD79BCREBBP (CBP)CRLF2 (TSLPR)CYLDEP300FAM46CIL7RIRF4JAK1JAK2JAK3MAP2K1MAP2K2 (MEK2)MAP3K1 (MEKK1)MCL1MYD88NFKBIA (IκBα, MAD3)PAX5PIK3CA (p110-alpha)PIK3R1 (p85-ALPHA)PTENPTPN11RELTNFAIP3TNFRSF14TP53 (p53)
Inflammatory Response
CEBPACSF1RJAK2MYD88PTGS2 (COX2)REL
Metabolism
AKT1AKT2AKT3ASXL2FHFLCNIDH1IDH2MTORPDK1PTGS2 (COX2)RICTORRPTORSDHASDHBSDHCSDHDTNFTSC2
RNA Splicing
DDX3XQKIRBM10SF3B1SMC1AU2AF1
Signal Transduction
ACVR1BAKT1AKT2AKT3ALKAMER1APCAXIN1AXLCBFBCDKN1A (p21CIP1, WAF1)CNKSR1CSF1RCYLDDDR2DNEREGFR (ERBB1)EPHA3EPHA5EPHA7EPHB1ERBB2 (HER-2, NEU)ERBB3ERBB4ERRFI1EWSR1FBXW7FGF19FGF3FGF4FGFBP1FGFR1FGFR2FGFR3FGFR4FLT1 (VEGFR1)FLT3FLT4 (VEGFR2)GABRA6GATA2GLI1GNA11GNA13GNAQGNASGRIN2AGSK3BHGFHNF1AIGF1RIGF2IGF2RIKBKEINPP4BIRF6IRS2JAK1JAK2JAK3KDR (VEGFR3)KIT (CD117)KRASLMO1LPAR2MAP2K1MAP2K2 (MEK2)MAP3K1 (MEKK1)MED12METNF1NOTCH1NOTCH2NOTCH3NOTCH4NRASNTRK1NTRK2NTRK3PDGFRAPDGFRBPIK3CA (p110-alpha)PIK3CBPIK3CGPIK3R1 (p85-ALPHA)PIK3R2 (p85-BETA)PLCG2PPP2R1APRKAR1APRKCIPTCH1PTENPTPN11RAF1RASA1RETRIT1RNF43ROS1SMAD2 (MADH2)SMAD3 (MADH3)SMAD4 (MADH4)SMOSOCS1SOS1SOX17SOX2SPENSRCSTAT3SUFUSYKTCF7L2TGFBR2TNFTNKS (TIN1)TRRAPTSC2TSHR
Transcription Factors
ARCEBPACICCUX1ERGESR1 (ERα)ETV6FBXW7FOXA1FOXL2FOXP1FUBP1GATA1GATA2GATA3GATA4GATA6GLI1HNF1AIRF4IRF6JUNKEAP1LZTR1MEF2BMEN1MITFMYBMYCMYCLMYCNMYOCDNFE2L2NKX2-1PAX5RB1RUNX1 (AML1)SMAD2 (MADH2)SMAD3 (MADH3)SMAD4 (MADH4)SOX10SOX17SOX2SOX9TBX3TCF7L2TP53 (p53)TP73WT1ZFHX3ZNF217
Ubiquitination
ASXL2BAP1BCORCDC27CUL3CUL4BDAXXMDM2PRKNRNF43
Unfolded Protein Response
HSP90AA1NFE2L2NPM1
Major Histocompatibility Complex Genes
B2MHLA-AHLA-BHLA-CHLA-EHLA-FHLA-GMR1
Antigen Presentation
ABCB9ACE2CALRCANXCTSBCTSLCTSSERAP1ERAP2IDEIFI30LGMNLNPEPNPEPPSNRD1PDIA3PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMA8PSMB1PSMB10PSMB11PSMB2PSMB3PSMB4PSMB5PSMB6PSMB7PSMB8PSMB9PSMC1PSMC2PSMC3PSMC4PSMC5PSMC6PSMD1PSMD10PSMD11PSMD12PSMD13PSMD14PSMD2PSMD3PSMD4PSMD5PSMD6PSMD7PSMD8PSMD9PSME1PSME2PSME3PSME4PSMF1PSMG1PSMG2PSMG3PSMG4TAP1 (ABCB2)TAP2 (ABCB3)TAPBPTAPBPLTOP1TPP2
Immune Checkpoint Molecules
VSIRCD200CD274 (PD-L1)CD274 (PD-L1)CD276CD40 (TNFRSF5)CD40LGCD48CD70CD80CD86ICOSLGITGAVITGB3LGALS9MICAMICBPDCD1LG2TNFRSF14TNFRSF9TNFSF14TNFSF18TNFSF4 (OX40L)TNFSF9VTCN1
Other Cancer-Related Genes
ALPK2COL5A1DIS3DMDFKBP9KELLRP1BMORC4MUC17TCP11L2TERCTERTTOP1

Product Resources

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Resources

Brochures & Guides (6)
Massively Parallel Sequencing Solutions for Human Identity
PDF (2MB)

Next-generation sequencing using QIAGEN’s QIAseq – a powerful tool for human identification


Exploring new frontiers with next-generation sequencing
PDF (2MB)
The QIAseq advantage – interactive product profile
PDF (2MB)
State-of-the-art technologies to fast-track and streamline NGS workflows
NGS for liquid biopsy research
PDF (260KB)
QIAGEN Paternity Testing Solutions
PDF (2MB)
Advanced sample collection, automation and STR solutions for kinship testing
Case study – QIAseq custom panels drive new insights into pancreatic cancer
PDF (195KB)
Expert insights
Template Files (7)
Using the QIAseq Targeted DNA Panels with CDIs Template for the LRM v3 Excel File from Illumina
ZIP (703KB)
Using the QIAseq Targeted DNA Panels with UDIs Template for the NovaSeq v1 Reagents
ZIP (471KB)
Using the QIAseq Targeted DNA Panels with UDIs Template for the NovaSeq v1.5 Reagents
ZIP (471KB)
Using the QIAseq Targeted DNA Panels with CDIs Template for the NovaSeq
ZIP (689KB)
Using the QIAseq Targeted DNA Panels with CDIs Template for the LRM v2 Excel File from Illumina
ZIP (703KB)
Using the QIAseq Targeted DNA Panels with UDIs Template for the Local Run Manager (LRM) v2 Excel File from Illumina
ZIP (477KB)
Using the QIAseq Targeted DNA Panels with UDIs Template for the Local Run Manager (LRM) v3 Excel File from Illumina
ZIP (477KB)
Application Notes (2)
Noninvasive prenatal paternity testing by means of SNP-based targeted sequencing barcoded with Unique Molecular Indices
PDF (435KB)

The use of UMIs as part of a QIAseq targeted sequencing panel

QIAseq SPE technology for Illumina: Redefining amplicon sequencing
PDF (238KB)
Safety Data Sheets (3)
Safety Data Sheets
Download Safety Data Sheets for QIAGEN product components.
QIAseq Targeted DNA HC Panel (96)
QIAseq Targeted DNA HC Panel (12)
Kit Handbooks (2)
QIAseq Targeted DNA Panel Handbook
PDF (3MB)
For ultrasensitive targeted next-generation sequencing (NGS) of DNA for Illumina NGS systems
QIAseq Targeted DNA Panel Handbook
PDF (3MB)
For ultrasensitive targeted next-generation sequencing (NGS) of DNA for Ion Torrent NGS systems
Certificates of Analysis (1)
Certificates of Analysis
Introducing the QIAseq Targeted DNA Human Tumor Mutational Burden Panel, a cutting-edge addition to our QIAseq Targeted DNA Panels lineup, specifically designed for NGS applications. This premium product offers unparalleled performance for researchers working with Human models. Leveraging advanced technology, the QIAseq Targeted DNA Human Tumor Mutational Burden Panel facilitates accurate and reliable results, making it an indispensable tool for your scientific investigations. Whether you're conducting NGS, or any other sophisticated analyses, this product from our QIAseq Targeted DNA Panels collection ensures optimal efficiency and reproducibility for Human studies. Embrace the future of research with QIAseq Targeted DNA Human Tumor Mutational Burden Panel and elevate your work to new heights.
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