Target List
Cell Surface & Cell Lineage Markers
CCR1CD164CD1DCD2CD34CD3DCD3GCD4CD44CD80CD86CD8ACSF1 (MCSF)DLL1 (DELTA1)FLT3LGFUT10FZD1CHST15IL31RAIL6ST (GP130)JAG1JAG2KDR (VEGFR3)KIT (CD117)KITLG (SCF)KITLG (SCF)LRMPMALNOTCH2NOTCH4PECAM1PTPRCSFXN1STIM2TEK (TIE-2, TIE2)TLR3TLR4CD27 (TNFRSF7)TNFSF11 (RANKL)
Cytokines & Growth Factors
Cytokines
CSF1 (MCSF)CSF2 (GM-CSF)FLT3LGIL10IL11IL12BIL25IL1AIL2IL20INHAINHBAPF4SPP1TNFSF11 (RANKL)
Growth Factors
CSF1 (MCSF)CSF2 (GM-CSF)IL10IL11IL1AIL2INHAINHBAJAG1JAG2KITLG (SCF)KITLG (SCF)SPP1VEGFA
Cell Cycle Regulators
Cell Cycle Arrest
INHAINHBANOTCH2
Other Regulators of the Cell Cycle
APCHDAC4HDAC5HDAC7HDAC9IL1AJAG2STAT1VEGFA
Blood Cell Activation
B-Cell Activation
HDAC4HDAC5HDAC7HDAC9
T-Cell Activation
CD2CD3DCD3GCD80CD86CD8A
Activation of Other Blood Cells
CD2IL11IL12BIL2IL31RAPF4TLR4
Cell Differentiation
B-Cell Differentiation
BLNKCHST15HDAC4HDAC5HDAC7HDAC9IL10IL11INHAINHBACD27 (TNFRSF7)
T-Cell Differentiation
CD2CD4CD80CD86IL12BIL2JAG2NOS2 (iNOS)SOCS5CD27 (TNFRSF7)
Differentiation of Other Blood Cell Types
ANGPT1CD3GCSF1 (MCSF)DLL1 (DELTA1)IL11IL20IL31RAINHAINHBAJAG1MALMAP4K1 (HPK1)NCOA6NOTCH1NOTCH2NOTCH4PAX5PF4SPP1TAL1TLR3TLR4TNFSF11 (RANKL)
Hematopoiesis Regulators
ASH2LCD164CSF1 (MCSF)DLL1 (DELTA1)FUT10IL10IL20IL31RAJAG1LMO2MMP9NOTCH2NOTCH4STIM2TRIM10
Signal Transduction
Notch Signaling
DLL1 (DELTA1)JAG1JAG2NOTCH2NOTCH4
WNT Signaling
APCFZD1LEF1WNT3A
JAK / STAT Signaling
IL31RASOCS5STAT1STAT3
Cell Surface Receptors
CCR1CD14CD2CD3DCD3GCD4CSF2 (GM-CSF)FZD1IL6ST (GP130)INHAINHBAPTPRCCD27 (TNFRSF7)
Transcription Factors & Regulators
ASH2LCBFBCD80CD86CEBPECEBPGETS1ETV6GATA1GATA2HDAC4HDAC5HDAC7HDAC9IL31RALEF1NCOA6NOTCH1NOTCH2NOTCH4PAX5RBPJRUNX1 (AML1)STAT1STAT3TAL1VAV1