Target List
Beta-Amyloid Generation, Oligomerization, Clearance & Degradation
Secretases
ADAM9APH1ABACE1BACE2CTSBNCSTNPSEN1PSEN2
Other Peptidases
IDEPLAT (TPA)PLAU (UPA)PLG
Endocytosis
APLP1APPLRP1LRP6LRP8
Other Beta-Amyloid Metabolism Genes
A2MACHEAPBB1APBB2APOEBCHEUBQLN1
Cytoskeleton Regulators
APOEMAP2MAPTPKP4PRKCI
Synaptic Formation
ACHEAPBA1 (MINT1)APBB1APBB2APOEBDNFCHAT
Lipid Metabolism
ABCA1APOA1APOECLUHSD17B10INSLPLLRP1LRP8SNCB
Apoptosis
APLP1APPCASP3CASP4CLUEP300ERN1IL1AMAPTMPONAE1PRKCAPRKCEPRKCZPSEN1PSEN2SNCA
Cell Cycle
APBB1APBB2CDK1CDK5CDKL1ERN1EP300IL1ANAE1PRKCA
Cell Signaling Molecules
WNT Signaling
GSK3AGSK3BLRP6
Notch Signaling
ADAM10APH1ANCSTNPSEN1PSEN2
G-Protein Coupled Receptor Signaling
APLP2GNAO1GNAZGNB1GNB4GNB5GNG11GNG3GNG4GNGT1GNGT2NTRK1NTRK2
Intracellular Signaling
APBA3APBB2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCIPRKCQPRKCZPSEN1PSEN2
Other Cell Signaling Molecules
GAP43GNB2IDEIL1AINSRNAE1PLAU (UPA)
Transcriptional Regulation
APBB1APBB2EP300ERN1
Oxidative Stress
HSD17B10MPOUQCRC1UQCRC2
Proteases & Protease Inhibitors
ADAM10APLP2APPCAPN1CTSCCTSDCTSGCTSLSERPINA3UQCRC2