A
Actin Cytoskeleton Signaling Actin Nucleation by ARP-WASP Complex Activation of IRF by Cytosolic Pattern Recognition Receptors Acute Myeloid Leukemia Signaling Acute Phase Response Signaling Adipogenesis pathway Adrenomedullin signaling pathway Agranulocyte Adhesion and Diapedesis Agrin Interactions at Neuromuscular Junction Airway Inflammation in Asthma Airway Pathology in Chronic Obstructive Pulmonary Disease Aldosterone Signaling in Epithelial Cells Allograft Rejection Signaling Altered T Cell and B Cell Signaling in Rheumatoid Arthritis AMPK Signaling Amyloid Processing Amyotrophic Lateral Sclerosis Signaling Androgen Signaling Angiopoietin Signaling Antigen Presentation Pathway Antioxidant Action of Vitamin C Antiproliferative Role of Somatostatin Receptor 2 Antiproliferative Role of TOB in T Cell Signaling Apelin Adipocyte Signaling Pathway Apelin Cardiac Fibroblast Signaling Pathway Apelin Cardiomyocyte Signaling Pathway Apelin Endothelial Signaling Pathway Apelin Liver Signaling Pathway Apelin Muscle Signaling Pathway Apelin Pancreas Signaling Pathway Apoptosis Signaling April Mediated Signaling Arsenate Detoxification I (Glutaredoxin) Aryl Hydrocarbon Receptor Signaling Assembly of RNA Polymerase I Complex Assembly of RNA Polymerase II Complex Assembly of RNA Polymerase III Complex Atherosclerosis Signaling ATM Signaling Autoimmune Thyroid Disease Signaling Autophagy Axonal Guidance Signaling
C
Calcium Signaling Calcium-induced T Lymphocyte Apoptosis cAMP-mediated signaling Cancer Drug Resistance By Drug Efflux Cardiac Hypertrophy Signaling Cardiac β-adrenergic Signaling Cardiomyocyte Differentiation via BMP Receptors Caveolar-mediated Endocytosis Signaling CCR3 Signaling in Eosinophils CCR5 Signaling in Macrophages CD27 Signaling in Lymphocytes CD28 Signaling in T Helper Cells CD40 Signaling Cdc42 Signaling CDK5 Signaling Cell Cycle Control of Chromosomal Replication Cell Cycle Regulation by BTG Family Proteins Cell Cycle: G1/S Checkpoint Regulation Cell Cycle: G2/M DNA Damage Checkpoint Regulation Cellular Effects of Sildenafil (Viagra) Ceramide Biosynthesis Ceramide Signaling Chemokine Signaling Cholecystokinin/Gastrin-mediated Signaling Chronic Myeloid Leukemia Signaling Circadian Rhythm Signaling Clathrin-mediated Endocytosis Signaling Cleavage and Polyadenylation of Pre-mRNA CNTF Signaling Coagulation System Colorectal Cancer Metastasis Signaling Communication between Innate and Adaptive Immune Cells Complement System Corticotropin Releasing Hormone Signaling CREB Signaling in Neurons Crosstalk between Dendritic Cells and Natural Killer Cells CTLA4 Signaling in Cytotoxic T Lymphocytes CXCR4 Signaling Cyclins and Cell Cycle Regulation Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells
D
Death Receptor Signaling Dendritic Cell Maturation Differential Regulation of Cytokine Production in Intestinal Epithelial Cells by IL-17A and IL-17F Differential Regulation of Cytokine Production in Macrophages and T Helper Cells by IL-17A and IL-17F Diphthamide Biosynthesis DNA damage-induced 14-3-3σ Signaling DNA Double-Strand Break Repair by Homologous Recombination DNA Double-Strand Break Repair by Non-Homologous End Joining DNA Methylation and Transcriptional Repression Signaling Docosahexaenoic Acid (DHA) Signaling Dopamine Receptor Signaling Dopamine-DARPP32 Feedback in cAMP Signaling
E
EGF Signaling Eicosanoid Signaling EIF2 Signaling Embryonic Stem Cell Differentiation into Cardiac Lineages Endocannabinoid Cancer Inhibition Pathway Endocannabinoid Developing Neuron Pathway Endometrial Cancer Signaling Endoplasmic Reticulum Stress Pathway Endothelin-1 Signaling eNOS Signaling Ephrin A Signaling Ephrin B Signaling Ephrin Receptor Signaling Epithelial Adherens Junction Signaling ErbB Signaling ErbB2-ErbB3 Signaling ErbB4 Signaling ERK/MAPK Signaling ERK5 Signaling Erythropoietin Signaling Estrogen Receptor Signaling Estrogen-Dependent Breast Cancer Signaling Estrogen-mediated S-phase Entry Eumelanin Biosynthesis Extrinsic Prothrombin Activation Pathway
G
G Beta Gamma Signaling G Protein Signaling Mediated by Tubby G-Protein Coupled Receptor Signaling GABA Receptor Signaling GADD45 Signaling Gap Junction Signaling GDNF Family Ligand-Receptor Interactions Germ Cell-Sertoli Cell Junction Signaling Glioblastoma Multiforme Signaling Glioma Invasiveness Signaling Glioma Signaling Glucocorticoid Receptor Signaling Glutamate Receptor Signaling Glutaryl-CoA Degradation GM-CSF Signaling GNRH Signaling GP6 Signaling Pathway GPCR-Mediated Integration of Enteroendocrine Signaling Exemplified by an L Cell GPCR-Mediated Nutrient Sensing in Enteroendocrine Cells Graft-versus-Host Disease Signaling Granulocyte Adhesion and Diapedesis Granzyme A Signaling Granzyme B Signaling Growth Hormone Signaling Gustation Pathway Gα12/13 Signaling Gαi Signaling Gαq Signaling Gαs Signaling
H
Hematopoiesis from Multipotent Stem Cells Hematopoiesis from Pluripotent Stem Cells Hepatic Cholestasis Hepatic Fibrosis / Hepatic Stellate Cell Activation HER-2 Signaling in Breast Cancer Hereditary Breast Cancer Signaling HGF Signaling HIF1α Signaling HIPPO signaling HMGB1 Signaling Human Embryonic Stem Cell Pluripotency Huntington's Disease Signaling Hypoxia Signaling in the Cardiovascular System Hypusine Biosynthesis
I
iCOS-iCOSL Signaling in T Helper Cells IGF-1 Signaling IL-1 Signaling IL-10 Signaling IL-12 Signaling and Production in Macrophages IL-15 Production IL-15 Signaling IL-17 Signaling IL-17A Signaling in Airway Cells IL-17A Signaling in Fibroblasts IL-17A Signaling in Gastric Cells IL-2 Signaling IL-22 Signaling IL-3 Signaling IL-4 Signaling IL-6 Signaling IL-7 Signaling Pathway IL-8 Signaling IL-9 Signaling ILK Signaling Induction of Apoptosis by HIV1 Inflammasome pathway Inhibition of Angiogenesis by TSP1 Inhibition of Matrix Metalloproteases iNOS Signaling Insulin Receptor Signaling Integrin Signaling Interferon Signaling Intrinsic Prothrombin Activation Pathway Iron homeostasis signaling pathway Isoleucine Degradation I
M
Macropinocytosis Signaling Maturity Onset Diabetes of Young (MODY) Signaling Mechanisms of Viral Exit from Host Cells Melanocyte Development and Pigmentation Signaling Melanoma Signaling Melatonin Degradation III Melatonin Signaling MIF Regulation of Innate Immunity MIF-mediated Glucocorticoid Regulation Mismatch Repair in Eukaryotes Mitochondrial Dysfunction Mitotic Roles of Polo-Like Kinase Molecular Mechanisms of Cancer Molybdenum Cofactor Biosynthesis Mouse Embryonic Stem Cell Pluripotency MSP-RON Signaling Pathway mTOR Signaling Myc Mediated Apoptosis Signaling
N
NADH Repair Natural Killer Cell Signaling NER Pathway Netrin Signaling Neuregulin Signaling Neuroinflammation Signaling Pathway Neuropathic Pain Signaling In Dorsal Horn Neurons Neuroprotective Role of THOP1 in Alzheimer's Disease Neurotrophin/TRK Signaling NF-κB Activation by Viruses NF-κB Signaling NGF Signaling Nitric Oxide Signaling in the Cardiovascular System nNOS Signaling in Neurons nNOS Signaling in Skeletal Muscle Cells Non-Small Cell Lung Cancer Signaling Notch Signaling NRF2-mediated Oxidative Stress Response Nucleotide Excision Repair Pathway Nur77 Signaling in T Lymphocytes
P
P2Y Purinergic Receptor Signaling Pathway p38 MAPK Signaling p53 Signaling p70S6K Signaling PAK Signaling Pancreatic Adenocarcinoma Signaling Parkinson's Signaling Pathogenesis of Multiple Sclerosis Paxillin Signaling PCP pathway PDGF Signaling PEDF Signaling Phagosome Formation Phagosome Maturation Phospholipase C Signaling Phototransduction Pathway PI3K Signaling in B Lymphocytes PI3K/AKT Signaling PKCθ Signaling in T Lymphocytes Polyamine Regulation in Colon Cancer PPAR Signaling PPARα/RXRα Activation Primary Immunodeficiency Signaling Production of Nitric Oxide and Reactive Oxygen Species in Macrophages Prolactin Signaling Prostate Cancer Signaling Protein Kinase A Signaling Protein Ubiquitination Pathway PTEN Signaling PXR/RXR Activation
R
Rac Signaling RAN Signaling RANK Signaling in Osteoclasts RAR Activation Reelin Signaling in Neurons Regulation of Actin-based Motility by Rho Regulation of Cellular Mechanics by Calpain Protease Regulation of eIF4 and p70S6K Signaling Regulation of IL-2 Expression in Activated and Anergic T Lymphocytes Regulation of the Epithelial-Mesenchymal Transition Pathway Relaxin Signaling Remodeling of Epithelial Adherens Junctions Renal Cell Carcinoma Signaling Renin-Angiotensin Signaling Retinoic acid Mediated Apoptosis Signaling RhoA Signaling RhoGDI Signaling Role of BRCA1 in DNA Damage Response Role of CHK Proteins in Cell Cycle Checkpoint Control Role of Cytokines in Mediating Communication between Immune Cells Role of Hypercytokinemia/hyperchemokinemia in the Pathogenesis of Influenza Role of IL-17A in Arthritis Role of IL-17A in Psoriasis Role of IL-17F in Allergic Inflammatory Airway Diseases Role of JAK family kinases in IL-6-type Cytokine Signaling Role of JAK1 and JAK3 in γc Cytokine Signaling Role of JAK1, JAK2 and TYK2 in Interferon Signaling Role of JAK2 in Hormone-like Cytokine Signaling Role of Lipids/Lipid Rafts in the Pathogenesis of Influenza Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis Role of MAPK Signaling in the Pathogenesis of Influenza Role of NANOG in Mammalian Embryonic Stem Cell Pluripotency Role of NFAT in Cardiac Hypertrophy Role of NFAT in Regulation of the Immune Response Role of Oct4 in Mammalian Embryonic Stem Cell Pluripotency Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis Role of p14/p19ARF in Tumor Suppression Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses Role of PI3K/AKT Signaling in the Pathogenesis of Influenza Role of PKR in Interferon Induction and Antiviral Response Role of RIG1-like Receptors in Antiviral Innate Immunity Role of Tissue Factor in Cancer Role of WNT/GSK-3β Signaling in the Pathogenesis of Influenza
S
SAPK/JNK Signaling Semaphorin Signaling in Neurons Serotonin Receptor Signaling Sertoli Cell-Sertoli Cell Junction Signaling Signaling by Rho Family GTPases Sirtuin Signaling Pathway Small Cell Lung Cancer Signaling Sonic Hedgehog Signaling Sperm Motility Sphingosine-1-phosphate Signaling SPINK1 General Cancer Pathway SPINK1 Pancreatic Cancer Pathway STAT3 Pathway Sumoylation Pathway Superpathway of Melatonin Degradation Superpathway of Methionine Degradation Synaptic Long Term Depression Synaptic Long Term Potentiation Systemic Lupus Erythematosus Signaling
T
T Cell Receptor Signaling T Helper Cell Differentiation Tec Kinase Signaling Telomerase Signaling Telomere Extension by Telomerase Tetrahydrobiopterin Biosynthesis II TGF-β Signaling Th1 and Th2 Activation Pathway Th1 Pathway Th17 Activation Pathway Th2 Pathway The Visual Cycle Thrombin Signaling Thrombopoietin Signaling Thyroid Cancer Signaling Thyroid Hormone Biosynthesis Thyroid Hormone Metabolism I (via Deiodination) Thyronamine and Iodothyronamine Metabolism Tight Junction Signaling TNFR1 Signaling TNFR2 Signaling Toll-like Receptor Signaling TR/RXR Activation Transcriptional Regulatory Network in Embryonic Stem Cells TREM1 Signaling Tryptophan Degradation III (Eukaryotic) Tumoricidal Function of Hepatic Natural Killer Cells TWEAK Signaling Type I Diabetes Mellitus Signaling Type II Diabetes Mellitus Signaling