Target List
IL6 / STAT3 Signaling
STAT3 Activators
CXCL12EGFRIL10IL11IL17AIL21IL23AIL6
Cell Surface Receptors
CD4CD40CD80CSF3RCXCR4FASIL18R1IL1R1IL2RAIL6RIL6STLIFROSMRTNFRSF10BTNFRSF1ATNFRSF1B
Signaling Upstream of IL6 / STAT3
AKT1JAK2JAK3MAP2K1MAPK1MAPK14MAPK3MAPK8MTORMYCPIAS3RAC1SOCS1SOCS3SRCTYK2
Signaling Downstream of IL6 / STAT3
BAXBCL2CDC25ACDKN1AHGFMETPIM1STAT3
IL6 / STAT3 Signaling Target Genes
CCL2CCL5CD80CEBPDCXCL10CXCL12CXCL8IL10IL11IL12AIL17AIL1BIL21IL6MYCSOCS3
Cytokines
CCL2CCL3CCL4CCL5CD40LGCSF1CSF2CSF3CXCL10CXCL12CXCL8FASLGIL10IL11IL13IL15IL17AIL18IL1AIL1BIL2IL21IL22IL23AIL3IL4IL5IL6IL7IL9LIFLTAOSMTNFTNFSF10TNFSF11
NFκB Signaling
IKBKBNFKB1NFKBIARELATLR4