Target List
Toll-Like Receptors
Cd180Tlr1Tlr2Tlr3Tlr4Tlr5Tlr6Tlr7Tlr9
Pathogen-Specific Responses
Bacterial Response
Ccl2Cd14FosHmgb1HrasHspa1aIl10Il12aIl1bIl6Irak1JunLtaLy86NfkbiaPglyrp1Ptgs2RelaRipk2Rnf138Tlr2Tlr4Tlr6Tnfrsf1a
Viral Response
Eif2ak2Ifnb1IfngIl12aIl6Irf3LOC103694380RelaRnf138Tbk1Tlr3Tlr7
Fungal / Parasitic Response
HrasHspa1aTlr2
Toll-Like Receptor (TLR) Signaling
Negative Regulation of Toll-Like Receptor (TLR) Signaling
Tollip
TICAM1 (TRIF)-Dependent (MYD88-Independent) Signaling
Irf3LOC100910771Nr2c2Peli1Rnf138Tbk1Ticam2Tlr3Tlr4Traf6
MYD88-Dependent Signaling
Irak1Irak2LOC100910771Myd88Nr2c2Tlr1Tlr2Tlr4Tlr5Tlr6Tlr7Tlr9Traf6
Signaling Downstream of Toll-Like Receptors
NFκB Signaling
BtkCasp8ChukFaddIkbkbIl10Il1bIl1r1Irak1Irak2Irf3LOC100910771LOC100912618LOC103694380Ly86Map3k1Map4k4Nfkb1Nfkb2NfkbiaNfkbibNfkbil1NfrkbPparaRelRelaTnfrsf1aTnip2TraddUbe2n
JNK / p38 Signaling
FosIl1bJunKcnh8LOC100910771LOC103694380Map2k3Map2k4Map3k1Mapk8Mapk8ip3Mapk9
JAK / STAT Signaling
Ccl2Csf2Csf2Csf2IfngIl12aIl2Il6
Interferon Regulatory Factor (IRF) Signaling
Cxcl10Ifna5Ifnb1IfngIrf1Irf3Tbk1
Cytokine Signaling
Ccl2CebpbClec4eCsf3Il1aIl1bIl1r1Il6Il6rIrak1Irak2LOC103694380RelaTnfrsf1a
Regulation of Adaptive Immunity
Cd80Cd86Hspd1IfngIl10Il12aIl1bIl2LOC100910771Traf6
Toll-Like Receptor Interacting Proteins & Adaptors
BtkCd14Hmgb1HrasHspa1aHspd1Ly86MalMapk8ip3Myd88Peli1Pglyrp1Ripk2Rnf138Sarm1Ticam2Tollip
Downstream Effectors of Toll-Like Receptor Signaling
Casp8Eif2ak2FaddIrak1Irak2LOC100910771LOC100912618Nr2c2PparaTraf6Ube2n