Target List
Skeletal Development
Cartilage Condensation
BMP1BMPR1BCOL2A1SOX9
Ossification
ACVR1AHSGBGLAPBMP1BMP2BMP3BMP4BMP5BMP6BMP7BMPR1ABMPR1BBMPR2CDH11CHRDCOL1A1COL2A1CSF1CTSKDLX5EGFRFGF2FGFR2GDF10GLI1IGF1IGF1RIGF2IHHMMP2MMP8MMP9NOGRUNX2SMAD1SMAD3SOX9SP7SPP1TGFB1TGFB2TGFB3TNFSF11TWIST1
Osteoclast Differentiation
BGLAPCSF1TNFTNFSF11
Osteoblast Differentiation
ACVR1BGLAPBMP2BMP4BMP6BMP7BMPR1ABMPR1BBMPR2CHRDCOL1A1DLX5FGF2FGFR2GDF10GLI1IGF1IHHNOGRUNX2SMAD1SMAD3SP7SPP1TWIST1
Other Skeletal Development Genes
ALPLCOMPFGFR1TGFBR1TGFBR2
Bone Mineral Metabolism
Bone Mineralization
ACVR1AHSGBGLAPBMP2BMP4BMP6BMP7BMPR1ABMPR1BBMPR2FGFR2IGF1SMAD3SOX9TGFB1TGFB3TWIST1
Calcium Ion Binding & Homeostasis
ANXA5BGLAPCALCRCDH11COMPEGFFGF2ITGB1MMP2MMP8TGFB1VDR
Extracellular Matrix (ECM) Molecules
Collagens
COL10A1COL14A1COL15A1COL1A1COL1A2COL2A1COL3A1COL5A1
Extracellular Matrix (ECM) Protease Inhibitors
AHSGSERPINH1
Extracellular Matrix (ECM) Proteases
CTSKMMP10MMP2MMP8MMP9PHEX
Other Extracellular Matrix (ECM) Molecules
ALPLBGNFLT1
Cell Adhesion Molecules
Cell-Cell Adhesion
BMP1BMPR1BCDH11COL14A1COL2A1EGFRICAM1IHHITGB1SOX9TGFB1TNFTNFSF11VCAM1
Cell-Extracellular Matrix (ECM) Adhesion
CD36COL3A1CSF1ITGA1ITGA2ITGA3ITGAMITGB1SMAD3
Other Cell Adhesion Molecules
BGLAPCOL15A1COL5A1COMPFN1TNF
Growth Factors
CSF2CSF3EGFFGF1FGF2GDF10IGF1IGF2PDGFAVEGFAVEGFB
Transcription Factors
GLI1NFKB1RUNX2SMAD1SMAD2SMAD3SMAD4SMAD5SOX9TWIST1