Target List
Breast Cancer Classification Markers
Luminal A-C Breast Cancers
ESR1FOXA1GATA3KRT8KRT18SLC39A6TFF3XBP1
HER2-Like Breast Cancers
ERBB2GRB7
Basal-Like / Triple Negative Breast Cancers
BIRC5EGFRKRT5NOTCH1
Breast Cancer Metastasis to Lung
ID1MMP2PTGS2
Signal Transduction
Steroid Receptor-Mediated Signaling
ARBRCA1CCNE1CTNNB1ESR1ESR2IGF1KRT19PGRRB1
Hedgehog Signaling
BCL2CCND1GLI1SNAI2
Glucocorticoid Signaling
IGFBP3NME1NR3C1
Classical WNT Signaling
APCCCND1CTNNB1SFRP1
AKT & PI3 Kinase Signaling
AKT1ERBB2IGF1IGF1RPTEN
Notch Signaling
BIRC5NOTCH1
MAP Kinase Signaling
MAPK1MAPK3MAPK8TP73
Epithelial-to-Mesenchymal Transition (EMT)
CTNNB1NOTCH1SRCTGFB1TWIST1
Angiogenesis
CDH13CTNNB1EGFERBB2ID1IL6JUNNOTCH1PLAUPTENSERPINE1SLIT2THBS1VEGFA
Cell Adhesion Molecules
ADAM23APCBCL2CDH1CDH13CDKN2ACSF1CTNNB1EGFRERBB2PTENTGFB1THBS1
Proteases
ADAM23CST6CTSDMMP2MMP9PLAUPYCARD
Apoptosis
AKT1APCBADBCL2CDH1CDKN1ACDKN2AGSTP1IGF1IL6JUNMUC1NME1RARBSFNSFRP1TP53TP73TWIST1
Cell Cycle
APCBCL2CCNA1CCND1CCND2CCNE1CDK2CDKN1ACDKN1CCDKN2AJUNMKI67MYCPTENRASSF1RB1SFNTP53
DNA Damage & Repair
APCATMBRCA1BRCA2CCND1CDKN1AMAPK1MGMTMLH1SFNTP53TP73
Xenobiotic Transport
ABCB1ABCG2
Transcription Factors
ARCTNNB1ESR1ESR2FOXA1GATA3HIC1JUNMYCNOTCH1NR3C1PGRPRDM2RARBRB1TP53TP73XBP1