Target List
Fungal Pattern Recognition Receptors (PRRs)
Beta-Glycan Responsive
CD36CD5CLEC7AITGAMITGB2SCARF1TLR2
Mannose / Chitin Responsive
CD207CD209CHIACLEC6AMRC1TLR2TLR4
Other Fungal Pattern Recognition Receptors (PRRs)
COLEC12NLRP3NPTX1PTX3TLR9
Signal Transduction
Dectin-1 Signaling
BCL10CARD9CLEC7AMALT1PLCG2RAF1SYK
NFκB Signaling
BCL10CARD9CASP1CASP8CD40IKBKBIL10IL1BIRAK1IRAK4MALT1MAP3K7NFKB1NFKBIASTAT1TNF
Toll-Like Receptor (TLR) Signaling
CASP8CD14FOSIRAK1IRAK4ITGB2JUNMAP2K4MAP3K7MAPK14MAPK8MYD88NFKB1TIRAPTLR2TLR4TLR9TRAF6
Complement Signaling
C3C5AR1ITGAMITGB2LYNMBL2SYK
NOD-Like Receptor (NLR) Signaling
CARD9CASP1NLRP3PYCARD
Inflammation
C3CCL2CCL20CCL5CCR1CD14CD40CLEC7ACXCL1CXCL10CXCL11CXCL2CXCL9F3FOSIL10IL1AIL1BIL2IL23AIL6CXCL8ITGB2LYNMBL2MYD88NFKB1PTGS2TIRAPTLR2TLR4TLR9TNF
Phagocytosis
C3CD14CD36CLEC7ACOLEC12FCGR1AFCN1MBL2SFTPD
Genes Responsive to Specific Pathogenic Fungi
Candida albicans
CCL2CCL20CCL5CCR1CD14CD209CD83CLEC6ACLEC7ACSF2CSF3CXCL1CXCL10CXCL11CXCL2CXCL9FCGR1AFCGR3AIFNGIL12BIL18IL1AIL1BIL1R1IL23AIL6CXCL8MYD88NFKB1PTGS2SOCS3TLR2TNF
Aspergillus fumigatus
C3CASP1CASP8CCL2CCL20CCL5CCR1CD14CD40CD83CLEC6ACLEC7ACSF2CSF3CXCL1CXCL10CXCL11CXCL2CXCL9F2RL1F3FCGR1AFCGR2AFCN1IFNGIL10IL12AIL12BIL18IL1AIL1BIL1R1IL6CXCL8JUNMALT1MAPK14MBL2MYD88NFKBIAPTGS2PTPN6PTX3SFTPDSOCS3ST3GAL5STAT1SYKTLR2TLR4TLR9TNF
Cryptococcus neoformans
C3CD5CCL2CD40SOCS3