Target List
Bone Remodeling & BMP Signaling
ADCY10ALOX12ALOX15ALOX5ALPLBGLAPBMP2CLCN7COL1A1COL1A2COMTCRTAPCTSKENPP1HSD11B1IGF1ITGA1ITGB3MMP2MTHFRNFATC1NOGNOS3P2RX7PLOD2RUNX2SFRP1SOSTSPARCSPP1STAT1TIMP2TWIST1WNT10BWNT3A
Calciotropic Hormones & Receptors
ARCALCACALCRCASRCYP17A1CYP19A1DBPESR1ESR2ESRRANR3C1PRLPTHPTH1RPTHLHSHBGTSHRVDR
Cytokines, Growth Factors & Receptors
BMP2BMP7CD40CNR2FGFR1FGFR2GHRHIGFBP2IL15IL6IL6RP3H1LRP1LRP5LRP6LTALTBP2MSTNNPYTGFB1TNFAIP3TNFRSF11ATNFRSF11BTNFRSF1BTNFSF11VEGFA
Osteoblast Activity & Differentiation
ALPLBGLAPBMP2RUNX2
RANK / RANKL / OPG Signaling
TNFRSF11ATNFRSF11BTNFSF11
WNT / β-Catenin Signaling
DKK1LRP1LRP5LRP6SFRP4SOSTTWIST1WNT10BWNT3A
Other Osteoporosis Genes
ACP5CA2LEPMAB21L2