Target List
Apoptosis
AKT1BCL2BCL2L1BCL2L1BCL2L1CASP8CASP9FASLG
Necrosis
CYLDGRB2MAGPARP2PVRTXNL4B
DNA Damage & Repair
ATMBRCA1CDKN1AERCC2MDM2RAD51
Mitochondrial Energy Metabolism
ARRDC3ASB1CYB561D1DNAJB1HSPA1AHSPA1BSLC25A25
Fatty Acid Metabolism (β-Oxidation)
ACADMACADVLACOX1CPT1ACPT1BCPT2
Oxidative Stress & Antioxidant Response
AKR1C2FHL2GCLMHMOX1NCOA7NQO1SLC7A11
Heat Shock Response
HSF1HSP90B1HSPA4HSPA8HSPB1HSPD1
Endoplasmic Reticulum Stress & Unfolded Protein Response
ADM2ASNSDNAJB9HERPUD1INHBETRIB3UHRF1
Cytochrome P450s & Phase I Drug Metabolism
CYP1A2CYP2B6CYP2C19CYP2C9CYP2D6
Steatosis
CD36FASNLPLPPARASCDSREBF1
Cholestasis
ABCB4ABCC2ABCC3ATP8B1SLC51APDYNRDX
Phospholipidosis
ASAH1HPNLSSSERPINA3SLC2A3TAGLNWIPI1
Immunotoxicity
ADH1CF2HPXLYZMETAP2MKI67NR5A2TRIM10